Evidence map›Paper›PMID 27131918›Full record

SynthesisClinical psychology review2016

Is hyperactivity ubiquitous in ADHD or dependent on environmental demands? Evidence from meta-analysis.

Michael J Kofler, Joseph S Raiker, Dustin E Sarver, Erica L Wells, Elia F Soto

Abstract readMeta-Analysis
In one paragraph

Synthesis in Clinical psychology review, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael J KoflerFlorida State University, Department of Psychology, 1107 W. Call Street, Tallahassee, FL 32306-4301, United States. Electronic address: kofler@psy.fsu.edu.
Joseph S RaikerFlorida International University | Department of Psychology Center for Children and Families 11200 SW 8th St. | Miami, FL 33199, United States.
Dustin E SarverUniversity of Mississippi Medical CenterDepartment of Pediatrics, Division of Child Development Center for Advancement of Youth (CAY) 2500 North State Street Jackson, MS 39216, United States.
Erica L WellsFlorida State University, Department of Psychology, 1107 W. Call Street, Tallahassee, FL 32306-4301, United States.
Elia F SotoFlorida State University, Department of Psychology, 1107 W. Call Street, Tallahassee, FL 32306-4301, United States.

Funding

Evaluating the Feasibility of Central Executive Training for Children with ADHD- Administrative SupplementR34MH102499 · NIMH · FLORIDA STATE UNIVERSITY · PI KOFLER, MICHAEL J · 2014 to 2016
$737k
NIMH NIH HHS R34 MH102499
6 · The paper itself

Abstract

Hyperactivity, or excess gross motor activity, is considered a core and ubiquitous characteristic of ADHD. Alternate models question this premise, and propose that hyperactive behavior reflects, to a large extent, purposeful behavior to cope with environmental demands that interact with underlying neurobiological vulnerabilities. The present review critically evaluates the ubiquity and environmental modifiability of hyperactivity in ADHD through meta-analysis of 63 studies of mechanically measured activity level in children, adolescents, and adults with ADHD relative to typically developing groups. Random effects models corrected for publication bias confirmed elevated gross motor activity in ADHD (d=0.86); surprisingly, neither participant age (child vs. adult) nor the proportion of each ADHD sample diagnosed with the inattentive subtype/presentation moderated this effect. In contrast, activity level assessed during high cognitive load conditions in general (d=1.14) and high executive functioning demands in particular (d=1.39) revealed significantly higher effect sizes than activity level during low cognitive load (d=0.36) and in-class schoolwork (d=0.50) settings. Low stimulation environments, more rigorous diagnostic practices, actigraph measurement of movement frequency and intensity, and ADHD samples that included fewer females were also associated with larger effects. Overall, the results are inconsistent with DSM-5 and ADHD models that a) describe hyperactivity as ubiquitous behavior, b) predict a developmental decline in hyperactivity, or c) differentiate subtypes/presentations according to perceived differences in hyperactive behavior. Instead, results suggest that the presence and magnitude of hyperactive behavior in ADHD may be influenced to a considerable extent by environmental factors in general, and cognitive/executive functioning demands in particular.

Indexed as

AdultAge FactorsAttention Deficit Disorder with HyperactivityChildExecutive FunctionHumansPsychomotor AgitationSex Factors

Identifiers

PMID27131918
PMCPMC4902796

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.