Evidence map›Paper›PMID 27131897›Full record

ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2016

Magistral drugs in hospitalized newborns and children.

Agueda Cabral de Souza Pereira, Elaine Silva Miranda, Selma Rodrigues de Castilho, Débora Omena Futuro, Lenise Arneiro Teixeira, Geraldo Renato de Paula

Open access · diamondAbstract read
In one paragraph

Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Compounded medications for cardiovascular use in neonatology: an integrative review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Agueda Cabral de Souza PereiraUniversidade Federal Fluminense (UFF), Niterói, RJ, Brasil.
Elaine Silva MirandaUniversidade Federal Fluminense (UFF), Niterói, RJ, Brasil.
Selma Rodrigues de CastilhoUniversidade Federal Fluminense (UFF), Niterói, RJ, Brasil.
Débora Omena FuturoUniversidade Federal Fluminense (UFF), Niterói, RJ, Brasil.
Lenise Arneiro TeixeiraUniversidade Federal Fluminense (UFF), Niterói, RJ, Brasil.
Geraldo Renato de PaulaUniversidade Federal Fluminense (UFF), Niterói, RJ, Brasil. Electronic address: geraldopaula@vm.uff.br.
Universidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveStudy the use of magistral oral solutions and suspensions in infants and children at a university hospital.

methodsThis is a descriptive study based on the analysis of the assessed hospital's magistral drug request forms regarding the patients in the neonatal ICU, Obstetrics, Pediatrics and Pediatric Emergency from January 2012 to December 2013. The frequency of drug requests and dispensation was evaluated and the consumption of each active ingredient of the preparations was expressed as number of "infant defined daily dose" (iDDD) and of iDDD/100 bed-days.

resultsA total of 657 forms were analyzed - a monthly average of 27 pediatric preparations. The neonatal ICU accounted for 69.6% of these requests. Twenty-one drug items were used, of which the most common were folinic acid (88 requests), sulfadiazine (85) and captopril (73). The consumption of the active principle in these preparations varied in number of iDDD, from 7.5 (hydralazine) to 16,520.0 (folic acid), and in number of iDDD/100 bed-days in the neonatal ICU, from 0.1 (zinc sulfate) to 146.1 (folic acid).

conclusionsThe constant consumption of magistral oral solutions and suspensions by newborns and children of the assessed hospital indicates the need for such preparations as a pediatric therapeutic alternative in this hospital.

Indexed as

SolutionsSuspensionsAdministration, OralChildDrug CompoundingHospitalizationHospitals, UniversityHumansInfant, NewbornIntensive Care Units, NeonatalPrescription DrugsRetrospective StudiesPrescription DrugsSolutionsSuspensionsFractionated drugsMedicamentos fracionadosMedicamentos não licenciadosMedicamentos pediátricosMedication usePediatric medicationsUnlicensed drugsUso de medicamentos

Identifiers

PMID27131897
PMCPMC5176058
OpenAlexW2321689852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.