ReviewTrends in cognitive sciences2016
Reward Processing and Risk for Depression Across Development.
Review in Trends in cognitive sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06213883 (Characterizing Acute Exercise Response in Restrictive Eating Disorders), which is not on this map. Cited by 98 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Characterizing Acute Exercise Response in Restrictive Eating Disorders
Who cites it
98 citing papers in PubMed, 6 syntheses or guidelines pooled it, 190 citations in OpenAlex.
- Great Expectations: A Critical Review of and Suggestions for the Study of Reward Processing as a Cause and Predictor of Depression.Biological psychiatry · 2021Pooled it
- The functional neural architecture of dysfunctional reward processing in autism.NeuroImage. Clinical · 2021Pooled it
- Meta-analysis of reward processing in major depressive disorder reveals distinct abnormalities within the reward circuit.Translational psychiatry · 2019Pooled it
- Neuroimaging predictors of onset and course of depression in childhood and adolescence: A systematic review of longitudinal studies.Developmental cognitive neuroscience · 2019Pooled it
- Reward Processing in Depression: A Conceptual and Meta-Analytic Review Across fMRI and EEG Studies.The American journal of psychiatry · 2018Pooled it
- The effects of ketamine on dopaminergic function: meta-analysis and review of the implications for neuropsychiatric disorders.Molecular psychiatry · 2018Pooled it
- Consummatory deficits in close social reward predict inflammation-induced depressed mood.Psychoneuroendocrinology · 2026Trial
- Word usage in spontaneous speech as a predictor of depressive symptoms among youth at high risk for mood disorders.Journal of affective disorders · 2023Trial
- The thrill of victory: Savoring positive affect, psychophysiological reward processing, and symptoms of depression.Emotion (Washington, D.C.) · 2022Trial
- Neural Indicators of Anhedonia: Predictors and Mechanisms of Treatment Change in a Randomized Clinical Trial in Early Childhood Depression.Biological psychiatry · 2019Trial
- Neural Correlates of Reward Processing in Depressed and Healthy Preschool-Age Children.Journal of the American Academy of Child and Adolescent Psychiatry · 2016Trial
- Low Emotional Awareness and Altered Frontostriatal Functional Connectivity During Reward Processing Prospectively Predict Depressive Symptoms in At-Risk Youth.Journal of child and adolescent psychopharmacology · 2026Article
- Executive functions as a transdiagnostic endophenotype in developmental psychopathology.Molecular psychiatry · 2026Review
- Reimagining the Biopsychosocial Model: Transdiagnostic Factors to Precision Psychiatry.Biological psychiatry global open science · 2026Article
- Transdiagnostic divergent neural development of reward anticipation in early adolescents at risk for depression and psychosis.Developmental cognitive neuroscience · 2026Article
- Executive Dysfunction and Depression Risk in Adolescence: Functional-MRI Analysis of Transient Network States During a Working Memory Task.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Parental anhedonic versus non-anhedonic depressive symptoms and children's reward processing.Journal of experimental child psychology · 2026Article
- Psychobiological mechanisms underlying the association between early life stress and depression in adolescence.Molecular psychiatry · 2026Review
- Links Between Altered Feedback Learning and Symptoms of Depression: Insights From the FRN and Feedback-Locked N170.Psychophysiology · 2026Article
- Structural covariance network in the striatum is modulated by non-suicidal self-injury in adolescents with major depressive disorder.BMC psychiatry · 2025Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Striatal response to reward has been of great interest in the typical development and psychopathology literatures. These parallel lines of inquiry demonstrate that although typically developing adolescents show robust striatal response to reward, adolescents with major depressive disorder (MDD) and those at high risk for MDD show a blunted response to reward. Understanding how these findings intersect is crucial for the development and application of early preventative interventions in at-risk children, ideally before the sharp increase in the rate of MDD onset that occurs in adolescence. Robust findings relating blunted striatal response to reward and MDD risk are reviewed and situated within a normative developmental context. We highlight the need for future studies investigating longitudinal development, specificity to MDD, and roles of potential moderators and mediators.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.