ArticleGait & posture2016
Effects of Levodopa on Postural Strategies in Parkinson's disease.
Article in Gait & posture, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Effects of Oral Levodopa on Balance in People with Idiopathic Parkinson's Disease.Journal of Parkinson's disease · 2023Pooled it
- Wearable Inertial Sensors to Assess Standing Balance: A Systematic Review.Sensors (Basel, Switzerland) · 2019Pooled it
- Strategic alterations of posture are delayed in Parkinson's disease patients during deep brain stimulation.Scientific reports · 2021Trial
- Individual and combined effects of a cognitive task, light finger touch, and vision on standing balance in older adults with mild cognitive impairment.Aging clinical and experimental research · 2020Trial
- The Effects of Deep Brain Stimulation on Balance in Parkinson's Disease as Measured Using Posturography-A Narrative Review.Brain sciences · 2025Review
- Levodopa-induced dyskinesia alters postural control in people with Parkinson's disease.Journal of biomechanics · 2024Article
- Objective estimation of m-CTSIB balance test scores using wearable sensors and machine learning.Frontiers in digital health · 2024Article
- Clinical Static Balance Assessment: A Narrative Review of Traditional and IMU-Based Posturography in Older Adults and Individuals with Incomplete Spinal Cord Injury.Sensors (Basel, Switzerland) · 2023Review
- Article
- A Public Data Set With Ground Reaction Forces of Human Balance in Individuals With Parkinson's Disease.Frontiers in neuroscience · 2022Article
- Post-Drive Standing Balance of Vehicle Passengers Using Wearable Sensors: The Effect of On-Road Driving and Task Performance.Sensors (Basel, Switzerland) · 2021Article
- Fifteen Years of Wireless Sensors for Balance Assessment in Neurological Disorders.Sensors (Basel, Switzerland) · 2020Review
- Evaluation of Wearable Sensor Devices in Parkinson's Disease: A Review of Current Status and Future Prospects.Parkinson's disease · 2020Review
- Sensory Re-weighting for Postural Control in Parkinson's Disease.Frontiers in human neuroscience · 2019Article
- Validity and repeatability of inertial measurement units for measuring gait parameters.Gait & posture · 2017Article
- How Wearable Sensors Can Support Parkinson's Disease Diagnosis and Treatment: A Systematic Review.Frontiers in neuroscience · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Altered postural control and balance are major disabling issues of Parkinson's disease (PD). Static and dynamic posturography have provided insight into PD's postural deficits; however, little is known about impairments in postural coordination. We hypothesized that subjects with PD would show more ankle strategy during quiet stance than healthy control subjects, who would include some hip strategy, and this stiffer postural strategy would increase with disease progression. We quantified postural strategy and sway dispersion with inertial sensors (one placed on the shank and one on the posterior trunk at L5 level) while subjects were standing still with their eyes open. A total of 70 subjects with PD, including a mild group (H&Y≤2, N=33) and a more severe group (H&Y≥3, N=37), were assessed while OFF and while ON levodopa medication. We also included a healthy control group (N=21). Results showed an overall preference of ankle strategy in all groups while maintaining balance. Postural strategy was significantly lower ON compared to OFF medication (indicating more hip strategy), but no effect of disease stage was found. Instead, sway dispersion was significantly larger in ON compared to OFF medication, and significantly larger in the more severe PD group compared to the mild. In addition, increased hip strategy during stance was associated with poorer self-perception of balance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.