ArticleJournal of the National Cancer Institute2016
Racial Differences in Quantitative Measures of Area and Volumetric Breast Density.
Article in Journal of the National Cancer Institute, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
60 citing papers in PubMed, 94 citations in OpenAlex.
- Targeting Matrix Stiffness and Mechanotransduction in Breast Cancer: Implications for Emerging Therapies.International journal of molecular sciences · 2026Review
- Association between Participant Characteristics and Breast Parenchymal Texture Variation among Postmenopausal Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Non-Medical Gender Affirming Practices Among Transgender Individuals: A Systematic Review on the Health Implications of Chest Binding and Genital Tucking.International journal of sexual health : official journal of the World Association for Sexual Health · 2026Article
- Racial differences in quantitative background parenchymal enhancement on breast magnetic resonance imaging.Cancer · 2025Article
- Robust evaluation of tissue-specific radiomic features for classifying breast tissue density grades.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Where are we now and where do we go from here? A structured literature review analyzing the current state of breast density research trends and discussions.Cancer causes & control : CCC · 2025Review
- Interplay of BMI and volumetric breast density measures and breast cancer risk for black and white women.Breast cancer research : BCR · 2025Article
- Reproductive determinants of mammographic density in black women.Cancer causes & control : CCC · 2025Article
- Racial Differences in Screening Eligibility by Breast Density After State-Level Insurance Expansion.JAMA network open · 2025Article
- Radiomic Parenchymal Phenotypes of Breast Texture from Mammography and Association with Risk of Breast Cancer.Radiology · 2025Article
- Mammographic density and breast cancer risk among Black American women.International journal of cancer · 2025Article
- Concordant and discordant breast density patterns by different approaches for assessing breast density and breast cancer risk.Breast cancer research and treatment · 2025Article
- Collagen architecture in triple negative breast cancer.PloS one · 2025Article
- AI's ongoing impact: Implications of AI's effects on health equity for women's healthcare providers.Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- Lifecourse Growth and Development Determinants of Mammographic Density in Black Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Effect of patient age and breast parenchymal density on Breast Imaging-Reporting and Data System (BIRADS-4) Subcategorization.Pakistan journal of medical sciences · 2024Article
- Screening mammography performance according to breast density: a comparison between radiologists versus standalone intelligence detection.Breast cancer research : BCR · 2024Article
- Generalisable deep learning method for mammographic density prediction across imaging techniques and self-reported race.Communications medicine · 2024Article
- Disparities in Breast Cancer Care-How Factors Related to Prevention, Diagnosis, and Treatment Drive Inequity.Healthcare (Basel, Switzerland) · 2024Review
- Status of breast cancer detection in young women and potential of liquid biopsy.Frontiers in oncology · 2024Review
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundIncreased breast density is a strong risk factor for breast cancer and also decreases the sensitivity of mammographic screening. The purpose of our study was to compare breast density for black and white women using quantitative measures.
methodsBreast density was assessed among 5282 black and 4216 white women screened using digital mammography. Breast Imaging-Reporting and Data System (BI-RADS) density was obtained from radiologists' reports. Quantitative measures for dense area, area percent density (PD), dense volume, and volume percent density were estimated using validated, automated software. Breast density was categorized as dense or nondense based on BI-RADS categories or based on values above and below the median for quantitative measures. Logistic regression was used to estimate the odds of having dense breasts by race, adjusted for age, body mass index (BMI), age at menarche, menopause status, family history of breast or ovarian cancer, parity and age at first birth, and current hormone replacement therapy (HRT) use. All statistical tests were two-sided.
resultsThere was a statistically significant interaction of race and BMI on breast density. After accounting for age, BMI, and breast cancer risk factors, black women had statistically significantly greater odds of high breast density across all quantitative measures (eg, PD nonobese odds ratio [OR] = 1.18, 95% confidence interval [CI] = 1.02 to 1.37, P = .03, PD obese OR = 1.26, 95% CI = 1.04 to 1.53, P = .02). There was no statistically significant difference in BI-RADS density by race.
conclusionsAfter accounting for age, BMI, and other risk factors, black women had higher breast density than white women across all quantitative measures previously associated with breast cancer risk. These results may have implications for risk assessment and screening.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.