Evidence map›Paper›PMID 27130455›Full record

ArticleBMC pulmonary medicine2016

A retrospective analysis to identify predictors of COPD-related rehospitalization.

Melissa H Roberts, Emmanuelle Clerisme-Beaty, Chris M Kozma, Andrew Paris, Terra Slaton, Douglas W Mapel

Abstract readMulticenter Study
In one paragraph

Article in BMC pulmonary medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Hospital Readmission Due to Chronic Obstructive Pulmonary Disease: A Longitudinal Study.International journal of health policy and management · 2022
    Article
  8. Predictors of short-term COPD readmission.Internal and emergency medicine · 2022
    Observational
  9. Article
  10. Article
  11. Article
  12. Early hospital readmission increases short and long - term mortality in patients with interstitial lung disease.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Multi-morbidities are Not a Driving Factor for an Increase of COPD-Related 30-Day Readmission Risk.International journal of chronic obstructive pulmonary disease · 2020
    Observational
  17. Article
  18. Article
  19. Article
  20. Predicting Acute Exacerbations in Chronic Obstructive Pulmonary Disease.Journal of managed care & specialty pharmacy · 2018
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Melissa H RobertsLovelace Clinic Foundation, 2309 Renard Place SE, Suite 103, Albuquerque, NM, 87106, USA. MRoberts@lcfresearch.org.
Emmanuelle Clerisme-BeatyBoehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, USA.
Chris M KozmaCK Consulting, St. Helena Island, SC, USA.
Andrew ParisVigilytics LLC, Victor, NY, USA.
Terra SlatonTLS Statistics, West Columbia, SC, USA.
Douglas W MapelLovelace Clinic Foundation, 2309 Renard Place SE, Suite 103, Albuquerque, NM, 87106, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) is often associated with recurrent hospitalizations. This study aimed to identify factors related to COPD rehospitalization.

methodsA national US claims database was used to identify patients, aged ≥40 years, hospitalized for COPD. Their first COPD-related hospital admission date in 2009 was set as the index date, with post-discharge COPD-related rehospitalization assessed for 180 days post-index date. Data were analyzed for: 1) all eligible patients in whom early COPD-related rehospitalization was evaluated (1-30 days post discharge; all-patient cohort) and 2) a patient subset not rehospitalized early in whom late COPD-related rehospitalization was evaluated (>30 days post discharge to 180 days post-index date; late cohort). Logistic regressions controlling for age and sex assessed potential COPD-related rehospitalization predictors. Variables from the 360-day pre-index period and index hospitalization were evaluated for each cohort, and 30-day post-discharge variables evaluated for the late cohort.

resultsOf 3612 patients with an index hospitalization, 4.8 % (174) had an early COPD-related rehospitalization, and of the remaining 3438 patients, 13.7 % (471) had a late COPD-related rehospitalization. Several pre-index variables were predictive of early COPD-related rehospitalization including: pneumonia; comorbidities; COPD-related drug therapies; and prior hospitalizations. In patients not rehospitalized early, the strongest predictor of late COPD-related rehospitalization was pre-index COPD-related hospitalization (OR = 3.64 [P < 0.001]). The strongest index hospitalization factors predictive of late COPD-related rehospitalization were use of steroids (any route: OR = 1.62 [P = 0.007]) and nebulizers (OR = 1.65 [P = 0.007]); neither predicted early COPD-related rehospitalization. Generally, factors predicting COPD-related rehospitalization were similar in both cohorts.

conclusionsSeveral pre-index variables were associated with COPD-related rehospitalization. A strong predictor of COPD-related rehospitalization was prior hospitalization during the pre-index period, particularly with a primary COPD diagnosis, whilst other predictive factors related to increased COPD severity; these may be useful indicators for COPD-related rehospitalization risk assessment. Some factors, e.g., recurrent pneumonia and exacerbations, may be modifiable.

Indexed as

AgedAge FactorsFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient ReadmissionPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsUnited StatesChronic obstructive pulmonary disease (COPD)ComorbidityExacerbationsReadmission predictorsRehospitalizationUtilization

Identifiers

PMID27130455
PMCPMC4851802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.