ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2016
Lower relapse rates with good post-transplant outcome in alcoholic liver disease: Experience from a living donor liver transplant center.
Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Alcohol Consumption Post-Liver Transplantation: A Cross-Sectional Study.GE Portuguese journal of gastroenterology · 2023Article
- Liver Transplant Outcomes in India.Clinical liver disease · 2022Review
- Quality of life 5 years following liver transplantation.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Article
- Management of Alcohol Use Disorder in Patients With Alcoholic Liver Disease.Journal of clinical and experimental hepatologyReview
- Poor Outcomes after Recidivism in Living Donor Liver Transplantation for Alcohol-Related Liver Disease.Journal of clinical and experimental hepatologyArticle
- Prevalence of Modifiable Risk Factors for de novo Malignancies After Living Donor Liver Transplantation.Journal of clinical and experimental hepatologyArticle
- Recurrence of Primary Disease After Adult Liver Transplant - Risk Factors, Early Diagnosis, Management, and Prevention.Journal of clinical and experimental hepatologyReview
- Recidivism in Liver Transplant Recipients for Alcohol-related Liver Disease.Journal of clinical and experimental hepatologyReview
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPost-transplant relapse is a major factor influencing the long-term outcome in alcoholic liver disease (ALD) patients.
aimsThe aim of this study was to evaluate the relapse rates following living donor liver transplantation (LDLT) in patients with ALD in the Indian context with strong family support.
methodsOf 458 patients who underwent LDLT for ALD, 408 were included in the study. Post-transplant relapse was determined by information provided by the patient and/or family by means of outpatient and e-mail questionnaire, supported by clinical/biochemical parameters/liver histopathology.
resultsAll except one were males, with a mean age of 46.9 ± 8.5 years. The overall rate of relapse was 9.5 % at 34.7 months (interquartile range (IQR) 15-57.6), lower than that reported in the literature from the West. The relapse rate was higher in patients with a shorter duration of pre-transplant abstinence (17.4 % and 15.4 % for recipients with pre-transplant abstinence of <3 and <6 months, respectively, p < 0.05). The overall survival was 88.5 % at 3 years. Of 39 patients with relapse, 16 (41 %) were occasional drinkers, 14 (35.8 %) were moderate drinkers, and 9 (23 %) were heavy drinkers. All the heavy drinkers presented with features of graft dysfunction.
conclusionsGood results can be obtained following LDLT for ALD, with significantly lower relapse rates in our setup as compared to the West.
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