ArticleProgress in brain research2016
Neurovascular coupling and energy metabolism in the developing brain.
Article in Progress in brain research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed.
- Multimodal EEG-MRI Neuroimaging in Schizophrenia-A Systematic and Mechanistic Review.Journal of clinical medicine · 2026Review
- Developmental human brain connectome from fetal stage to early childhood.Developmental cognitive neuroscience · 2026Review
- Face perception and impact of face masks at 6 months post-term age in preterm and term infants (The BabyFace Study).Scientific reports · 2026Article
- The emergence of the language system in the toddler brain.bioRxiv : the preprint server for biology · 2026Article
- How to design real-world functional near-infrared spectroscopy studies: a primer.Neurophotonics · 2026Article
- Assessment of cortical activity, functional connectivity, and neuroplasticity in cerebral palsy using functional near-infrared spectroscopy: A scoping review.Developmental medicine and child neurology · 2025Article
- Cerebral blood flow and energy demand: imaging insights into neurovascular function.Neurophotonics · 2025Review
- Dynamic changes in the structure and function of brain mural cells around chronically implanted microelectrodes.Biomaterials · 2025Article
- Development of perivascular astrocyte processes.Frontiers in neuroscience · 2025Review
- Creative music therapy in preterm infants effects cerebrovascular oxygenation and perfusion.Scientific reports · 2024Article
- Neonatal neural responses to novelty related to behavioral inhibition at 1 year.Developmental psychology · 2024Article
- Functional connectivity of the pediatric brain.Neuroradiology · 2024Review
- Ecological functional near-infrared spectroscopy in mobile children: using short separation channels to correct for systemic contamination during naturalistic neuroimaging.Neurophotonics · 2024Article
- Near-infrared spectroscopy monitoring of neonatal cerebrovascular reactivity: where are we now?Pediatric research · 2024Review
- Advanced rehabilitation in ischaemic stroke research.Stroke and vascular neurology · 2024Review
- Characterizing Large-Scale Human Circuit Development with In Vivo Neuroimaging.Cold Spring Harbor perspectives in biology · 2024Review
- The neural correlates of response inhibition across the transition from infancy to toddlerhood: An fNIRS study.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Article
- Functional neuroimaging of responses to multiple sensory stimulations in newborns with perinatal asphyxia.Translational pediatrics · 2023Article
- Arousal state transitions occlude sensory-evoked neurovascular coupling in neonatal mice.Communications biology · 2023Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
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Abstract
In the adult brain, increases in local neural activity are almost always accompanied by increases in local blood flow. However, many functional imaging studies of the newborn and developing human brain have observed patterns of hemodynamic responses that differ from adult responses. Among the proposed mechanisms for the observed variations is that neurovascular coupling itself is still developing in the perinatal brain. Many of the components thought to be involved in actuating and propagating this hemodynamic response are known to still be developing postnatally, including perivascular cells such as astrocytes and pericytes. Both neural and vascular networks expand and are then selectively pruned over the first year of human life. Additionally, the metabolic demands of the newborn brain are still evolving. These changes are highly likely to affect early postnatal neurovascular coupling, and thus may affect functional imaging signals in this age group. This chapter will discuss the literature relating to neurovascular development. Potential effects of normal and aberrant development of neurovascular coupling on the newborn brain will also be explored, as well as ways to effectively utilize imaging techniques that rely on hemodynamic modulation such as fMRI and NIRS in younger populations.
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