ArticleJournal of physiological anthropology2016
Relationship between mitochondrial haplogroup and physiological responses to hypobaric hypoxia.
Article in Journal of physiological anthropology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Review
- Endocrine, inflammatory and immune responses and individual differences in acute hypobaric hypoxia in lowlanders.Scientific reports · 2023Article
- Individual variations and sex differences in hemodynamics and percutaneous arterial oxygen saturation (SpOJournal of physiological anthropology · 2022Article
- Could cardiac autonomic modulation be an objective method to identify hypobaric hypoxia symptoms at 25.000ft among Brazilian military airmen?Frontiers in physiology · 2022Article
- Mitochondrial Heteroplasmy Shifting as a Potential Biomarker of Cancer Progression.International journal of molecular sciences · 2021Review
- Individual variations and sex differences in hemodynamics with percutaneous arterial oxygen saturation (SpOJournal of physiological anthropology · 2020Article
- Current health status and its risk factors of the Tsarang villagers living at high altitude in the Mustang district of Nepal.Journal of physiological anthropology · 2018Article
- Association of EGLN1 genetic polymorphisms with SpOJournal of physiological anthropology · 2018Article
- Muscle activities during walking and running at energetically optimal transition speed under normobaric hypoxia on gradient slopes.PloS one · 2017Article
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Authors and funding
5 authors.
Funding
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Abstract
We aimed to investigate the relationship between mtDNA polymorphism and physiological responses to hypobaric hypoxia. The study included 28 healthy male students, consisting of 18 students in haplogroup D and 10 in haplogroup M7+G. Measurement sensors were attached to the participants for approximately 30 min in an environment with a temperature of 28 °C. After resting for 15 min, the programmed operation of the hypobaric chamber decreased the atmospheric pressure by 11.9 Torr every minute to simulate an increase in altitude of 150 m until 9.7 Torr (equivalent to 2500 m) and then decreased 9.7 Torr every minute until 465 Torr (equivalent to 4000 m). At each altitude, the pressure was maintained for 15 min and various measurements were taken. Haplogroup D showed higher SpO2 (p < 0.05) and significantly higher SpO2 during the pressure recovery period when compared with haplogroup M7+G. The distal skin temperature was higher in haplogroup D when compared with M7+G. These results suggested that haplogroup D maintained SpO2 at a higher level with higher peripheral blood flow during acute hypobaric exposure.
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