Evidence map›Paper›PMID 27130174›Full record

ReviewMolecular biotechnology2016

Biosensors for the Diagnosis of Celiac Disease: Current Status and Future Perspectives.

Katharina Anne Scherf, Rachele Ciccocioppo, Miroslav Pohanka, Kvetoslava Rimarova, Radka Opatrilova, Luis Rodrigo, Peter Kruzliak

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Quality and Agronomic Trait Analyses of Pyramids Composed of Wheat GenesInternational journal of molecular sciences · 2023
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Katharina Anne ScherfGerman Research Centre for Food Chemistry, Leibniz Institut, Freising, Germany.
Rachele CiccocioppoClinica Medica I, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
Miroslav PohankaFaculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic.
Kvetoslava RimarovaDepartment of Public Health and Hygiene, Faculty of Medicine, Pavol Jozef Safarik University, Kosice, Slovakia.
Radka OpatrilovaDepartment of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic.
Luis RodrigoDepartment of Gastroenterology, Central University Hospital of Asturias (HUCA), Oviedo, Spain.
Peter KruzliakLaboratory of Structural Biology and Proteomics, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Palackeho tr 1946/1, 612 42, Brno, Czech Republic. kruzliakpeter@gmail.com.
University of Veterinary Sciences Brno · CZHospital Universitario Central de Asturias · ESLeibniz-Institute for Food Systems Biology at the Technical University of Munich · DEUniversity of Defence · CZUniversity of Pavia · ITUniversity of Pavol Jozef Šafárik · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) is an autoimmune enteropathy initiated and sustained by the ingestion of gluten in genetically susceptible individuals. It is caused by a dysregulated immune response toward both dietary antigens, the gluten proteins of wheat, rye, and barley, and autoantigens, the enzyme tissue transglutaminase (TG2). The small intestine is the target organ. Although routine immunochemical protocols for a laboratory diagnosis of CD are available, faster, easier-to-use, and cheaper analytical devices for CD diagnosis are currently unavailable. This review focuses on biosensors, consisting of a physicochemical transducer and a bioreceptor, as promising analytical tools for diagnosis of CD and other diseases. Examples of recently developed biosensors as well as expectations for future lines of research and development in this field are presented.

Indexed as

AntibodiesBiosensing TechniquesCeliac DiseaseElectrochemical TechniquesGliadinGTP-Binding ProteinsHumansImmunohistochemistryProtein Glutamine gamma Glutamyltransferase 2TransglutaminasesAntibodiesGliadinGTP-Binding ProteinsProtein Glutamine gamma Glutamyltransferase 2TransglutaminasesAntibodyBiosensorsCeliac diseaseDiagnosisELISAImmunochemistry

Identifiers

PMID27130174
OpenAlexW2344939846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.