Evidence map›Paper›PMID 27130043›Full record

ArticleEndocrine-related cancer2016

HIF2A gain-of-function mutations detected in duodenal gangliocytic paraganglioma.

Zhengping Zhuang, Chunzhang Yang, Ales Ryska, Yuan Ji, Yingyong Hou, Sky D Graybill, Petra Bullova, Irina A Lubensky, Günter Klöppel, Karel Pacak

Abstract readLetter
In one paragraph

Article in Endocrine-related cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhengping ZhuangSurgical Neurology BranchNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
Chunzhang YangNeuro-Oncology BranchNational Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Ales RyskaThe Fingerland Department of PathologyCharles University Medical Faculty Hospital, Hradec Kralove, Czech Republic.
Yuan JiDepartment of PathologyZhongshan Hospital, Fudan University, Shanghai, China.
Yingyong HouDepartment of PathologyZhongshan Hospital, Fudan University, Shanghai, China.
Sky D GraybillSan Antonio Military Medical CenterFort Sam Houston, Texas, USA.
Petra BullovaSection on Medical NeuroendocrinologyEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA Department of Molecular Medicine Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovakia.
Irina A LubenskyCancer Diagnosis ProgramDivision of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Günter KlöppelConsultation Center for Pancreas and Neuroendocrine TumorsDepartment of Pathology, Technical University Munich, Munich, Germany.
Karel PacakSection on Medical NeuroendocrinologyEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA karel@mail.nih.gov.

Funding

Diagnosis, Pathophysiology And Molecular Biology of Pheochromocytoma and ParagangliomaZIAHD008735 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PACAK, KAREL · 2009 to 2024
$28.4M
Molecular Pathogenesis of NeoplasiaZIANS003052 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI HEISS, JOHN · 2009 to 2025
$20.7M
Hypoxia signaling in cancer developmentZIABC011773 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ZHUANG, ZHENGPING · 2017 to 2025
$13.0M
Intramural NIH HHS ZIA HD008735
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Basic Helix-Loop-Helix ProteinsDuodenal NeoplasmsEndothelial PAS Domain-Containing Protein 1FemaleHumansMutationParagangliomaBasic Helix-Loop-Helix ProteinsEndothelial PAS Domain-Containing Protein 1

Identifiers

PMID27130043
PMCPMC4899235

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.