SynthesisReviews in endocrine & metabolic disorders2016
A Genome-Wide Association Study in isolated populations reveals new genes associated to common food likings.
Synthesis in Reviews in endocrine & metabolic disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Strong association between the 12q24 locus and sweet taste preference in the Japanese population revealed by genome-wide meta-analysis.Journal of human genetics · 2020Pooled it
- Genetic Variants Influencing Taste Perception and Food Preferences: Current Evidence.Nutrients · 2026Review
- Differences in smell and taste performance and food liking between patients with stroke and healthy controls.Scientific reports · 2025Article
- Associations of CD36 rs1761667 with Fat and Umami Food Perception, Diet Quality, and BMI in Two European Studies.Foods (Basel, Switzerland) · 2025Article
- A Genome-Wide Association Study of Taste Liking in the Danish Population.The Journal of nutrition · 2025Article
- Article
- Association Between Dietary Taste Preferences and Primary Ovarian Insufficiency: A Mendelian Randomization Study.International journal of women's health · 2025Article
- Genetic determinants of food preferences: a systematic review of observational studies.BMC nutrition · 2024Article
- Regulator of G-Protein Signalling 9: A New Candidate Gene for Sweet Food Liking?Foods (Basel, Switzerland) · 2023Article
- Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association.Circulation · 2023Review
- Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.Nature communications · 2022Article
- Sensory Capacities and Eating Behavior: Intriguing Results from a Large Cohort of Italian Individuals.Foods (Basel, Switzerland) · 2022Article
- Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association.Circulation · 2021Article
- Obesity Genomics and Metabolomics: a Nexus of Cardiometabolic Risk.Current cardiology reports · 2020Review
- A Brief Review of Genetic Approaches to the Study of Food Preferences: Current Knowledge and Future Directions.Nutrients · 2019Review
- A genome-wide association study of bitter and sweet beverage consumption.Human molecular genetics · 2019Article
- Genetic determinants of beverage consumption: Implications for nutrition and health.Advances in food and nutrition research · 2019Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Food preferences are the first factor driving food choice and thus nutrition. They involve numerous different senses such as taste and olfaction as well as various other factors such as personal experiences and hedonistic aspects. Although it is clear that several of these have a genetic basis, up to now studies have focused mostly on the effects of polymorphisms of taste receptor genes. Therefore, we have carried out one of the first large scale (4611 individuals) GWAS on food likings assessed for 20 specific food likings belonging to 4 different categories (vegetables, fatty, dairy and bitter). A two-step meta-analysis using three different isolated populations from Italy for the discovery step and two populations from The Netherlands and Central Asia for replication, revealed 15 independent genome-wide significant loci (p < 5 × 10(-8)) for 12 different foods. None of the identified genes coded for either taste or olfactory receptors suggesting that genetics impacts in determining food likings in a much broader way than simple differences in taste perception. These results represent a further step in uncovering the genes that underlie liking of common foods that in the end will greatly help understanding the genetics of human nutrition in general.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.