Trial reportTrials2016
Effectiveness of medical hypnosis for pain reduction and faster wound healing in pediatric acute burn injury: study protocol for a randomized controlled trial.
Trial report in Trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Procedural Pain Management by Multimodal Sedation Analgesia Combining Hypnosis in Children With Congenital Heart Disease: a Randomized Non-inferiority Trial.
The Effect of Therapeutic Story on Pain, Fear and Anxiety Levels in Children With Burn Dressing
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Effects of non-pharmacological interventions on pain intensity of children with burns: A systematic review and meta-analysis.International wound journal · 2023Pooled it
- American Burn Association Guidelines on the Management of Acute Pain in the Adult Burn Patient: A Review of the Literature, a Compilation of Expert Opinion, and Next Steps.Journal of burn care & research : official publication of the American Burn Association · 2020Guideline
- Systematic review of clinical outcome reporting in randomised controlled trials of burn care.BMJ open · 2019Pooled it
- Effects of resilience training for mothers on maternal resilience and children's pain in pediatric burn units in a randomized controlled trial.Scientific reports · 2025Trial
- The effects of three kinds of non-steroidal anti-inflammatory drugs on postoperative pain and on the serum levels of tumour necrosis factor-α and substance P in paediatric patients following orthopaedic hip surgery.Archives of medical science : AMS · 2026Article
- Clinical hypnosis in pediatric care: An adjunctive tool or therapeutic illusion.World journal of experimental medicine · 2025Review
- Metabolic and Hormonal Changes in Pediatric Burn Patients: Mechanisms, Evidence, and Care Strategies.European burn journal · 2025Review
- Pathophysiology and management of burn injury-induced pain.Burns open : an international open access journal for burn injuries · 2025Article
- Hypnosis in Burn Care: Efficacy, Applications, and Implications for Austere Settings.European burn journal · 2024Article
- [A cross-sectional survey and analysis of influencing factors on the occurrence of post-burn psychological stress disorder in preschool children].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2024Article
- Optimizing burn wound procedural pain control, efficiency, and satisfaction through integrated nurse and physician education.Burns : journal of the International Society for Burn Injuries · 2024Review
- Review
- Evidence-based practical guideline for procedural pain management and sedation for burn pediatrics patients undergoing wound care procedures.Annals of medicine and surgery (2012) · 2022Review
- Modern Aspects of Burn Injury Immunopathogenesis and Prognostic Immunobiochemical Markers (Mini-Review).Biotech (Basel (Switzerland)) · 2022Review
- [Expert consensus on the application of nitrous oxide and oxygen mixed inhalation for sedation and analgesia technology in burn surgery (2021 version)].Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns · 2021Article
- Investigation on the Neural Mechanism of Hypnosis-Based Respiratory Control Using Functional MRI.Contrast media & molecular imaging · 2018Article
- Cryopreserved cultured epithelial allografts for pediatric deep partial dermal burns: Early wound closure and suppression of scarring.Regenerative therapy · 2017Article
- Population Profile of Children in Romania Affected by Burns.Current health sciences journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBurns and the associated wound care procedures can be extremely painful and anxiety-provoking for children. Burn injured children and adolescents are therefore at greater risk of experiencing a range of psychological reactions, in particular posttraumatic stress disorder, which can persist for months to years after the injury. Non-pharmacological intervention is critical for comprehensive pain and anxiety management and is used alongside pharmacological analgesia and anxiolysis. However, effective non-pharmacological pain and anxiety management during pediatric burn procedures is an area still needing improvement. Medical hypnosis has received support as a technique for effectively decreasing pain and anxiety levels in adults undergoing burn wound care and in children during a variety of painful medical procedures (e.g., bone marrow aspirations, lumbar punctures, voiding cystourethrograms, and post-surgical pain). Pain reduction during burn wound care procedures is linked with improved wound healing rates. To date, no randomized controlled trials have investigated the use of medical hypnosis in pediatric burn populations. Therefore this study aims to determine if medical hypnosis decreases pain, anxiety, and biological stress markers during wound care procedures; improves wound healing times; and decreases rates of traumatic stress reactions in pediatric burn patients. METHODS/
designThis is a single-center, superiority, parallel-group, prospective randomized controlled trial. Children (4 to 16 years, inclusive) with acute burn injuries presenting for their first dressing application or change are randomly assigned to either the (1) intervention group (medical hypnosis) or (2) control group (standard care). A minimum of 33 participants are recruited for each treatment group. Repeated measures of pain, anxiety, stress, and wound healing are taken at every dressing change until ≥95 % wound re-epithelialization. Further data collection assesses impact on posttraumatic stress symptomatology, speed of wound healing, and parent perception of how easy the dressing change is for their child. DISCUSSION: Study results will elucidate whether the disease process can be changed by using medical hypnosis with children to decrease pain, anxiety, and stress in the context of acute burn wounds.
trial registrationAustralian New Zealand Clinical Trials Registry ACTRN12615000419561.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.