Evidence map›Paper›PMID 27129568›Full record

SynthesisSurgical endoscopy2016

Laparoscopic repair of hiatus hernia: Does mesh type influence outcome? A meta-analysis and European survey study.

Jeremy R Huddy, Sheraz R Markar, Melody Z Ni, Mario Morino, Edoardo M Targarona, Giovanni Zaninotto, George B Hanna

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 117 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Observational
  7. Evaluation of the safety and effectiveness of crural reinforcement with bio-aHernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  8. Article
  9. 3D mesh-augmented hiatal hernia repair in patients with GERD: A 3-year single-center experience.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  10. Article
  11. One-year outcomes of biological mesh in hiatal hernia repair: a real-world study.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Trends in outcomes of 862 giant hiatus hernia repairs over 30 years.Hernia : the journal of hernias and abdominal wall surgery · 2023
    Article
  19. Antireflux Surgery's Lifespan: 20 Years After Laparoscopic Fundoplication.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Jeremy R HuddyDivision of Surgery, Department of Surgery and Cancer, Imperial College London, Academic Surgical Unit, 10th Floor, QEQM Building, St Mary's Hospital, South Wharf Road, London, W2 1NY, UK.
Sheraz R MarkarDivision of Surgery, Department of Surgery and Cancer, Imperial College London, Academic Surgical Unit, 10th Floor, QEQM Building, St Mary's Hospital, South Wharf Road, London, W2 1NY, UK.
Melody Z NiDivision of Surgery, Department of Surgery and Cancer, Imperial College London, Academic Surgical Unit, 10th Floor, QEQM Building, St Mary's Hospital, South Wharf Road, London, W2 1NY, UK.
Mario MorinoDepartment of Surgical Sciences, University of Torino, Turin, Italy.
Edoardo M TargaronaDepartment of General Surgery and Cancer, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Giovanni ZaninottoDivision of Surgery, Department of Surgery and Cancer, Imperial College London, Academic Surgical Unit, 10th Floor, QEQM Building, St Mary's Hospital, South Wharf Road, London, W2 1NY, UK.
George B HannaDivision of Surgery, Department of Surgery and Cancer, Imperial College London, Academic Surgical Unit, 10th Floor, QEQM Building, St Mary's Hospital, South Wharf Road, London, W2 1NY, UK. g.hanna@imperial.ac.uk.
St Mary's Hospital · GBHospital de Sant Pau · ESImperial College London · GBUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSynthetic mesh (SM) has been used in the laparoscopic repair of hiatus hernia but remains controversial due to reports of complications, most notably esophageal erosion. Biological mesh (BM) has been proposed as an alternative to mitigate this risk. The aim of this study is to establish the incidence of complications, recurrence and revision surgery in patients following suture (SR), SM or BM repair and undertake a survey of surgeons to establish a perspective of current practice.

methodsAn electronic search of EMBASE, MEDLINE and Cochrane database was performed. Pooled odds ratios (PORs) were calculated for discrete variables. To survey current practice an online questionnaire was sent to emails registered to the European Association for Endoscopic Surgery.

resultsNine studies were included, comprising 676 patients (310 with SR, 214 with SM and 152 with BM). There was no significant difference in the incidence of complications with mesh compared to SR (P = 0.993). Mesh significantly reduced overall recurrence rates compared to SR [14.5 vs. 24.5 %; POR = 0.36 (95 % CI 0.17-0.77); P = 0.009]. Overall recurrence rates were reduced in the SM compared to BM groups (12.6 vs. 17.1 %), and similarly compared to the SR group, the POR for recurrence was lower in the SM group than the BM group [0.30 (95 % CI 0.12-0.73); P = 0.008 vs. 0.69 (95 % CI 0.26-1.83); P = 0.457]. Regarding surgical technique 503 survey responses were included. Mesh reinforcement of the crura was undertaken by 67 % of surgeons in all or selected cases with 67 % of these preferring synthetic mesh to absorbable mesh. One-fifth of the respondents had encountered mesh erosion in their career.

conclusionsBoth SM and BM reduce rates of recurrence compared to SR, with SM proving most effective. Surgical practice is varied, and there remains insufficient evidence regarding the optimum technique for the repair of hiatal hernia.

Indexed as

Surgical MeshEuropeHernia, HiatalHumansLaparoscopyProstheses and ImplantsRecurrenceSurveys and QuestionnairesTreatment OutcomeHiatal herniaLaparoscopyMesh

Identifiers

PMID27129568
OpenAlexW2344921330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.