Observational studySurgical endoscopy2016
Laparoscopic management of large hiatus hernia: five-year cohort study and comparison of mesh-augmented versus standard crura repair.
Observational study in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07251010 (Phrenoesophageal Ligament Reconstruction With Mesh), which is not on this map. Cited by 22 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phrenoesophageal Ligament Reconstruction With Mesh: A New Approach to Hiatal Hernia Repair (Alinasser's Technique) for Adult Patients With Symptomatic Hiatus Hernia: A Randomized Controlled Trial
Who cites it
22 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- BIO-A versus Phasix biosynthetic mesh in minimally invasive hiatal hernia repair: systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2026Pooled it
- Management of symptomatic, asymptomatic, and recurrent hiatal hernia: a systematic review and meta-analysis.Surgical endoscopy · 2024Pooled it
- Cruroplasty with or without mesh? A systematic literature review with a novel time-organized proportion meta-analysis.Surgical endoscopy · 2024Pooled it
- Laparoscopic large hiatus hernia repair with mesh reinforcement versus suture cruroplasty alone: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2023Pooled it
- Does bioabsorbable mesh reduce hiatal hernia recurrence rates? A meta-analysis.Surgical endoscopy · 2023Pooled it
- Systematic review and meta-analysis of laparoscopic mesh versus suture repair of hiatus hernia: objective and subjective outcomes.Surgical endoscopy · 2017Pooled it
- Article
- Removal of the sac during surgery for the repair of "giant" paraesophageal hernias.World journal of gastrointestinal surgery · 2025Article
- Review
- Comparative anatomic and symptomatic recurrence outcomes of diaphragmatic suture cruroplasty versus biosynthetic mesh reinforcement in robotic hiatal and paraesophageal hernia repair.Surgical endoscopy · 2024Article
- Management of complicated diaphragmatic hernia in the acute setting: a WSES position paper.World journal of emergency surgery : WJES · 2023Review
- Hiatus hernia repair with a new-generation biosynthetic mesh: a 4-year single-center experience.Surgical endoscopy · 2023Article
- Surgical treatment of large and complicated hiatal hernias with the new resorbable mesh with hydrogel barrier (Phasix™ ST): a preliminary study.Journal of robotic surgery · 2023Article
- Surgical and clinical outcomes comparison of mesh usage in laparoscopic hiatal hernia repair.Surgical endoscopy · 2021Article
- Neutrophil-to-Lymphocyte Ratio (NLR) and Monocyte-to-Lymphocyte Ratio (MLR) Predict Clinical Outcome in Patients with Stage IIB Cervical Cancer.Journal of oncology · 2021Article
- Management of paraesophageal hernia review of clinical studies: timing to surgery, mesh use, fundoplication, gastropexy and other controversies.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2020Article
- Minimally invasive surgery for large hiatal hernia.Annals of gastroenterological surgery · 2019Review
- Routine use of mesh during hiatal closure is safe with no increase in adverse sequelae.Surgical endoscopy · 2018Article
- Crura augmentation with Bio-AHernia : the journal of hernias and abdominal wall surgery · 2017Observational
- Long-Term Patient-Reported Outcomes of Paraesophageal Hernia Repair.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate objective and subjective outcomes of patients undergoing laparoscopic repair of large hiatal hernia, either with or without resorbable mesh augmentation. The primary outcome of the study was anatomical recurrence rate as measured by endoscopy. Secondary outcomes were safety, efficacy, and long-term quality of life.
methodsThis was an observational cohort study. Patients who underwent laparoscopic repair of large (≥5 cm) type III hiatal hernia were included. Criteria of exclusion were previously failed hiatus hernia repair and emergency procedures. Patients were stratified into mesh group (mesh-augmented crura repair plus fundoplication) and non-mesh group (standard crura repair plus fundoplication). Preoperative and postoperative symptoms were assessed using the GERD-HRQL questionnaire. Upper gastrointestinal endoscopy was routinely performed between 6 and 12 months postoperatively and was repeated over the follow-up every 1-2 years or as needed. Anatomical hernia recurrence was defined as the maximum vertical length of stomach being at least 2 cm above the diaphragm.
resultsA total of 84 patients, 41 in the mesh group and 43 in the non-mesh group, operated between October 2009 and October 2014, were included in the study. All surgical procedures were completed laparoscopically. The median follow-up was 24 (IQR 29) months. There were 12 endoscopic recurrences, 4 in the mesh group and 8 in the non-mesh group. The five-year recurrence-free probability was similar in the two groups, but an earlier failure rate was noted in the non-mesh group at 12 months (p = 0.299). Three of the 12 patients with anatomical recurrence were symptomatic but did not require a reoperation. Univariate Cox proportional hazard analysis indicated that Toupet fundoplication may reduce the recurrence rate compared to Nissen fundoplication. No mesh-related complications occurred.
conclusionsLaparoscopic repair of large hiatal hernia is effective and durable. Crura reinforcement with a resorbable synthetic mesh is safe and may protect from early anatomical recurrence.
Indexed as
Identifiers
27129562What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.