Evidence map›Paper›PMID 27129460›Full record

Trial reportWorld journal of surgical oncology2016

Surgical anatomy of the internal thoracic lymph nodes in fresh human cadavers: basis for sentinel node biopsy.

Alfredo Carlos S D Barros, Lincon Jo Mori, Dolores Nishimura, Alfredo L Jacomo

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in World journal of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Ultrasound assessment of lymph nodes for staging of gynecological cancer: consensus opinion on terminology and examination technique.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alfredo Carlos S D BarrosDiscipline of Human Structural Topography, University of São Paulo Medical School, Av. Dr. Arnaldo, 455, São Paulo, SP, 01246-903, Brazil. clinab@terra.com.br.
Lincon Jo MoriDiscipline of Human Structural Topography, University of São Paulo Medical School, Av. Dr. Arnaldo, 455, São Paulo, SP, 01246-903, Brazil.
Dolores NishimuraMastology Department, Sírio-Libanês Hospital, Rua Adma Jafet, 91, São Paulo, SP, 01308-000, Brazil.
Alfredo L JacomoDiscipline of Human Structural Topography, University of São Paulo Medical School, Av. Dr. Arnaldo, 455, São Paulo, SP, 01246-903, Brazil.
Hospital Sírio-Libanês · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile the optimal management of early breast cancer patients with sentinel lymph node (SLN) involvement mapped in the internal thoracic chain is still debated, biopsy may be performed when surgeons select patients who are most likely to benefit. The aim of this study is to examine anatomical aspects of internal thoracic nodes (ITNs) to orientate SLN biopsy in the parasternal area.

methodsThis study was based on dissections of 29 female cadavers. The parameters analyzed were the number of intercostal spaces (ICSs) containing at least one ITN, mean number of nodes in each ICS, position of the ITNs in relation to the internal thoracic artery (ITA), number of retrocostal spaces (RCSs) containing at least one ITN, and mean number of nodes in each RCS.

resultsThe ICS that was most likely to have at least one ITN was the third, with 86.2% in the right side and 75.8% in the left side. In the second ICS, the rates were 69.2 and 73.6%, and in the fourth, the rates were 48.1 and 33.3%. In the third ICS, on both sides, the mean number of ITNs was the highest (1.2). A tendency of the nodes to be laterally located in the second ICS and medially located in the downward dissection was observed. Most of the RCSs did not present any nodes.

conclusionsThis study indicates that most of the second and third ICSs presented at least one ITN, and the mean number of nodes in the third space was greater. There is a tendency to find nodes medial to the artery downwards from the second to the fourth ICS. ITNs are generally located in ICSs, and the majority of RCSs did not contain any nodes.

Indexed as

Sentinel Lymph Node BiopsyAdultAgedAged, 80 and overBreast NeoplasmsCadaverFemaleFollow-Up StudiesHumansLymph Node ExcisionLymph NodesMiddle AgedNeoplasm StagingPrognosisThoracic WallYoung AdultBreast cancerInternal thoracic lymph nodesSentinel node biopsy

Identifiers

PMID27129460
PMCPMC4851783
OpenAlexW2344619816

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.