Evidence map›Paper›PMID 27129315›Full record

Trial reportBiological trace element research2016

Associations of Maternal Urinary Cadmium with Trimester-Specific Blood Pressure in Pregnancy: Role of Dietary Intake of Micronutrients.

C Osorio-Yañez, B Gelaye, R S Miller, D A Enquobahrie, A A Baccarelli, C Qiu, M A Williams

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Biological trace element research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Global inequities in dietary calcium intake during pregnancy: a systematic review and meta-analysis.BJOG : an international journal of obstetrics and gynaecology · 2019
    Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Urinary concentrations of environmental metals and associating factors in pregnant women.Environmental science and pollution research international · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

C Osorio-YañezDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard University, Kresge 500, 677 Huntington Avenue, Boston, MA, 02115, USA. cosorio@hsph.harvard.edu.
B GelayeDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard University, Kresge 500, 677 Huntington Avenue, Boston, MA, 02115, USA.
R S MillerCenter for Perinatal Studies, Swedish Medical Center, Seattle, WA, USA.
D A EnquobahrieCenter for Perinatal Studies, Swedish Medical Center, Seattle, WA, USA.
A A BaccarelliEnvironmental Health Department, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA, USA.
C QiuCenter for Perinatal Studies, Swedish Medical Center, Seattle, WA, USA.
M A WilliamsDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard University, Kresge 500, 677 Huntington Avenue, Boston, MA, 02115, USA.
Harvard University · USSwedish Medical Center · US

Funding

The Epidemiology of Marine Fatty Acids and PreeclampsiaR01HD032562 · NICHD · SWEDISH MEDICAL CENTER, FIRST HILL · PI WILLIAMS, MICHELLE A. · 1996 to 2006
$3.0M
Vitamin D related genes and developmental origins of cardiometabolic riskK01HL103174 · NHLBI · UNIVERSITY OF WASHINGTON · PI ENQUOBAHRIE, DANIEL ASMAMAW · 2010 to 2014
$661k
NHLBI NIH HHS K01 HL103174NICHD NIH HHS R01 HD032562
6 · The paper itself

Abstract

Previous studies revealed associations of urinary Cd (U-Cd), a chronic Cd exposure biomarker, with blood pressure (BP) in non-pregnant adults. However, the evidence regarding trimester-specific blood pressure in pregnancy and U-Cd and effect modification by dietary intake of micronutrients is scarce. We randomly selected 653 women from the Omega Study cohort. U-Cd was quantified by inductively coupled plasma mass spectrometry. Trimester-specific, systolic (SBP) and diastolic blood pressure (DBP) were determined employing standard protocols and mean arterial pressure (MAP) was also calculated. Associations of SBP, DBP, and MAP with U-Cd tertiles (≤0.21; 0.22-0.41; ≥0.42 μg/g Cr) were assessed using multivariable linear regression models. We also explored effect modification by pre-pregnancy BMI (≤25 or >25 kg/m

Indexed as

AdultBlood PressureCadmiumFemaleHumansMicronutrientsPregnancyPregnancy TrimestersCadmiumMicronutrientsBlood pressureMicronutrientsPregnancyUrinary cadmium

Identifiers

PMID27129315
PMCPMC6601343
OpenAlexW2344718435

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.