Evidence map›Paper›PMID 27129222›Full record

ReviewThe Journal of biological chemistry2016

Biofilm Exopolysaccharides of Pathogenic Fungi: Lessons from Bacteria.

Donald C Sheppard, P Lynne Howell

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 124 citations in OpenAlex.

  1. α-Mangostin attenuatesVirulence · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. TheJournal of fungi (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Characterization of Biofilm Formation by the DermatophyteJournal of fungi (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. Frontiers in microbiology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Identification of Compounds PreventingInternational journal of molecular sciences · 2023
    Article
  18. Pan-genome wide association study ofFrontiers in microbiology · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Donald C SheppardDepartments of Medicine, Microbiology and Immunology, Research Institute of the McGill University Health Centre, McGill University, Montréal, Québec H4A 3J1; Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, McGill University, Montréal, Québec H4A 3J1. Electronic address: don.sheppard@mcgill.ca.
P Lynne HowellProgram in Molecular Structure & Function, Research Institute, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada. Electronic address: howell@sickkids.ca.
Hospital for Sick Children · CAMcGill University Health Centre · CA

Funding

Enzyme therapeutics for biofilm prevention and disruptionR21AI119116 · NIAID · HOSPITAL FOR SICK CHLDRN (TORONTO) · PI HOWELL, PATRICIA LYNNE · 2015 to 2016
$445k
6 · The paper itself

Abstract

Exopolysaccharides play an important structural and functional role in the development and maintenance of microbial biofilms. Although the majority of research to date has focused on the exopolysaccharide systems of biofilm-forming bacteria, recent studies have demonstrated that medically relevant fungi such as Candida albicans and Aspergillus fumigatus also form biofilms during infection. These fungal biofilms share many similarities with those of bacteria, including the presence of secreted exopolysaccharides as core components of the extracellular matrix. This review will highlight our current understanding of fungal biofilm exopolysaccharides, as well as the parallels that can be drawn with those of their bacterial counterparts.

Indexed as

Antifungal AgentsAspergillus fumigatusBiofilmsCandida albicansFungal PolysaccharidesFungiHost-Pathogen InteractionsHumansMycosesPolysaccharides, BacterialAntifungal AgentsFungal PolysaccharidesPolysaccharides, Bacterialbacterial adhesionbiofilmcarbohydrate biosynthesisexopolysaccharideextracellular matrixpolysaccharide

Identifiers

PMID27129222
PMCPMC4933471
OpenAlexW2335901492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.