Evidence map›Paper›PMID 27128692›Full record

SynthesisInternational journal of occupational and environmental health2016

Effect of environmental exposure to hydrogen sulfide on central nervous system and respiratory function: a systematic review of human studies.

Eunjung Lim, Omar Mbowe, Angela S W Lee, James Davis

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in International journal of occupational and environmental health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 76 citations in OpenAlex.

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  12. Detection of HScientific reports · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eunjung Lima Biostatistics and Quantitative Health Sciences , John A. Burns School of Medicine, University of Hawaii , Honolulu , HI , USA.
Omar Mbowea Biostatistics and Quantitative Health Sciences , John A. Burns School of Medicine, University of Hawaii , Honolulu , HI , USA.
Angela S W Leeb Health Sciences Library , John A. Burns School of Medicine, University of Hawaii , Honolulu , HI , USA.
James Davisa Biostatistics and Quantitative Health Sciences , John A. Burns School of Medicine, University of Hawaii , Honolulu , HI , USA.
University of Hawaiʻi at Mānoa · US

Funding

UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Peter R Hoffmann · 2012 to 2026
$60.3M
RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MOKUAU, NOREEN, SHIRAMIZU, BRUCE T · 2012 to 2018
$21.1M
RESEARCH DESIGN, BIOSTATISTICS AND RESEARCH ETHICS COREG12MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI BERRY, MARLA J · 2012 to 2016
$13.0M
NIGMS NIH HHS P20 GM103466NIMHD NIH HHS G12 MD007601NIMHD NIH HHS U54 MD007584
6 · The paper itself

Abstract

backgroundAssessment of the health effects of low-level exposure to hydrogen sulfide (H2S) on humans through experiments, industrial, and community studies has shown inconsistent results.

objectiveTo critically appraise available studies investigating the effect of H2S on the central nervous system (CNS) and on respiratory function.

methodsA search was conducted in 16 databases for articles published between January 1980 and July 2014. Two researchers independently evaluated potentially relevant papers based on a set of inclusion/exclusion criteria.

resultsTwenty-seven articles met the inclusion criteria: 6 experimental, 12 industry-based studies, and 10 community-based studies (one article included both experimental and industry-based studies). The results of the systematic review varied by study setting and quality. Several community-based studies reported associations between day-to-day variations in H2S levels and health outcomes among patients with chronic respiratory conditions. However, evidence from the largest and better-designed community-based studies did not support that chronic, ambient H2S exposure has health effects on the CNS or respiratory function. Results from industry-based studies varied, reflecting the diversity of settings and the broad range of H2S exposures. Most studies did not have individual measurements of H2S exposure. DISCUSSION: The results across studies were inconsistent, justifying the need for further research.

Indexed as

Air PollutantsCentral Nervous SystemEnvironmental ExposureHumansHydrogen SulfideRespiratory Function TestsRespiratory Physiological PhenomenaAir PollutantsHydrogen SulfideCentral nervous systemGeothermalHydrogen sulfideRespiratory function

Identifiers

PMID27128692
PMCPMC4894269
OpenAlexW2345041929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.