Evidence map›Paper›PMID 27128670›Full record

ArticleMedicine and science in sports and exercise2016

Childhood Muscular Fitness Phenotypes and Adult Metabolic Syndrome.

Brooklyn J Fraser, Quan L Huynh, Michael D Schmidt, Terence Dwyer, Alison J Venn, Costan G Magnussen

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Article in Medicine and science in sports and exercise, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 7 pooled it
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 7 syntheses or guidelines pooled it, 87 citations in OpenAlex.

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  6. The Effect of Muscular Strength on Depression Symptoms in Adults: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Brooklyn J Fraser1Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, AUSTRALIA; 2Department of Kinesiology, University of Georgia, Athens, GA; 3George Institute for Global Health, Oxford Martin School and Nuffield Department of Obstetrics and Gynaecology, Oxford University, Oxford, England, UNITED KINGDOM; and 4Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, FINLAND.
Quan L Huynh
Michael D Schmidt
Terence Dwyer
Alison J Venn
Costan G Magnussen
University of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of this study is to determine whether childhood muscular fitness phenotypes (strength, endurance, and power) are independently associated with adult metabolic syndrome (MetS).

methodsWe conducted a longitudinal study including 737 participants who had muscular fitness measures in 1985 when age 9, 12, or 15 yr and attended follow-up in young adulthood 20 yr later when measures of MetS were collected. Childhood measures of muscular fitness included strength (right and left grip, leg, and shoulder extension and flexion), endurance (number of push-ups in 30 s), and power (distance of a standing long jump). A muscular fitness score was created using all individual muscular fitness phenotypes. In adulthood, waist circumference, blood pressure, HDL cholesterol, triglycerides, and glucose were measured. Adult outcomes were MetS defined using the harmonized definition and a continuous MetS risk score.

resultsParticipants with childhood muscular strength, muscular power, and combined muscular fitness score in the highest third had significantly lower relative risk (RR) for MetS and a lower continuous MetS score in adulthood independent of cardiorespiratory fitness than those in the lowest third (strength: RR = 0.21 (0.09, 0.49) β = -0.46 (-0.59, -0.34) power: RR = 0.26 (0.12, 0.60), β = -0.36 (-0.49, -0.23) fitness score: RR = 0.20 (0.09, 0.47), β = -0.45 (-0.58, -0.33)). However, adjustment for childhood waist circumference reduced the effect sizes for both adult outcomes by 17%-60%.

conclusionPhenotypes of childhood muscular fitness can be used to predict adult MetS independent of cardiorespiratory fitness. Although a large proportion of the effect of childhood muscular fitness on adult MetS is potentially being mediated by child waist circumference, these data suggest that promotion of muscular fitness among children might provide additional protection against developing adult MetS.

Indexed as

Muscle StrengthPhysical FitnessAdolescentAdultAustraliaChildFemaleHumansLongitudinal StudiesMaleMetabolic SyndromePhenotypePhysical EnduranceRisk Factors

Identifiers

PMID27128670
OpenAlexW2344518657

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.