ArticlePloS one2016
Comparative Transcriptomics Reveals Key Gene Expression Differences between Diapausing and Non-Diapausing Adults of Culex pipiens.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 67 citations in OpenAlex.
- The clock gene cycle synchronizes circadian metabolic oscillations uniquely in reproductively active Culex pipiens females.npj metabolic health and disease · 2026Article
- Tissue-specific transcriptomic and endocrine signatures of obligatory reproductive diapause in Eurygaster integriceps.Scientific reports · 2025Article
- A Head-Specific Transcriptomic Study Reveals Key Regulatory Pathways for Winter Diapause in the Mosquito Culex pipiens.Archives of insect biochemistry and physiology · 2025Article
- Article
- Light Pollution Disrupts Seasonal Differences in the Daily Activity and Metabolic Profiles of the Northern House Mosquito,Insects · 2023Article
- Seasonality influences key physiological components contributing toFrontiers in insect science · 2023Article
- Semi-field and surveillance data define the natural diapause timeline for Culex pipiens across the United States.Communications biology · 2022Article
- Comparative Transcriptome Analysis Reveals Molecular Insights in Overwintering Monochamus alternatus (Coleoptera: Cerambycidae).Journal of insect science (Online) · 2022Article
- Microbiome reduction prevents lipid accumulation during early diapause in the northern house mosquito, Culex pipiens pipiens.Journal of insect physiology · 2021Article
- Transcript Assembly and Quantification by RNA-Seq Reveals Significant Differences in Gene Expression and Genetic Variants in Mosquitoes of the Culex pipiens (Diptera: Culicidae) Complex.Journal of medical entomology · 2021Article
- Article
- miR-31-5p regulates cold acclimation of the wood-boring beetle Monochamus alternatus via ascaroside signaling.BMC biology · 2020Article
- Induction of long-lived potential aestivation states in laboratory An. gambiae mosquitoes.Parasites & vectors · 2020Article
- Understanding the regulation of overwintering diapause molecular mechanisms in Culex pipiens pallens through comparative proteomics.Scientific reports · 2019Article
- Diapause-associated changes in the lipid and metabolite profiles of the Asian tiger mosquito,The Journal of experimental biology · 2018Article
- Omics approaches to study juvenile hormone synthesis.Current opinion in insect science · 2018Review
- Global Transcriptome Sequencing Reveals Molecular Profiles of Summer Diapause Induction Stage of Onion Maggot,G3 (Bethesda, Md.) · 2018Article
- Evidence that microRNAs are part of the molecular toolkit regulating adult reproductive diapause in the mosquito, Culex pipiens.PloS one · 2018Article
- Housekeeping in Tephritid insects: the best gene choice for expression analyses in the medfly and the olive fly.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diapause is a critical eco-physiological adaptation for winter survival in the West Nile Virus vector, Culex pipiens, but little is known about the molecular mechanisms that distinguish diapause from non-diapause in this important mosquito species. We used Illumina RNA-seq to simultaneously identify and quantify relative transcript levels in diapausing and non-diapausing adult females. Among 65,623,095 read pairs, we identified 41 genes with significantly different transcript abundances between these two groups. Transcriptome divergences between these two phenotypes include genes related to juvenile hormone synthesis, anaerobic metabolism, innate immunity and cold tolerance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.