Evidence map›Paper›PMID 27127804›Full record

ArticleIEEE/SICE/RSJ International Conference on Multisensor Fusion and Integration for Intelligent Systems. IEEE/SICE/RSJ International Conference on Multisensor Fusion and Integration for Intelligent Systems2015

Force-Based Puncture Detection and Active Position Holding for Assisted Retinal Vein Cannulation.

Berk Gonenc, Nhat Tran, Cameron N Riviere, Peter Gehlbach, Russell H Taylor, Iulian Iordachita

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IEEE/SICE/RSJ International Conference on Multisensor Fusion and Integration for Intelligent Systems. IEEE/SICE/RSJ International Conference on Multisensor Fusion and Integration for Intelligent Systems, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Control Modes of Teleoperated Surgical Robotic System's Tools in Ophthalmic Surgery.IEEE transactions on medical robotics and bionics · 2025
    Article
  4. Review
  5. Robotic Assistance for Intraocular Microsurgery: Challenges and Perspectives.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2022
    Article
  6. Article
  7. Article
  8. Admittance Control for Robot Assisted Retinal Vein Micro-Cannulation under Human-Robot Collaborative Mode.ICCAS ... : International Conference on Control, Automation, and Systems. International Conference on Control, Automation, and Systems · 2017
    Article
  9. Article
  10. Robotic Vitreoretinal Surgery.Retina (Philadelphia, Pa.) · 2017
    Review
  11. Article
  12. Robot-assisted retinal vein cannulation with force-based puncture detection: Micron vs. the steady-hand eye robot.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Berk GonencCISST ERC at Johns Hopkins University, Baltimore, MD 21218 USA.
Nhat TranCISST ERC at Johns Hopkins University, Baltimore, MD 21218 USA.
Cameron N RiviereRobotics Institute at Carnegie Mellon University, Pittsburgh, PA 15213 USA.
Peter GehlbachWilmer Eye Institute at The Johns Hopkins School of Medicine, Baltimore, MD 21287 USA.
Russell H TaylorCISST ERC at Johns Hopkins University, Baltimore, MD 21218 USA.
Iulian IordachitaCISST ERC at Johns Hopkins University, Baltimore, MD 21218 USA.
Johns Hopkins University · USCarnegie Mellon University · US

Funding

A Microsurgical Assistant SystemR01EB007969 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI TAYLOR, RUSSELL H · 2008 to 2012
$5.7M
An Active Handheld MicromanipulatorR01EB000526 · NIBIB · CARNEGIE-MELLON UNIVERSITY · PI RIVIERE, CAMERON N · 2003 to 2017
$2.6M
NIBIB NIH HHS R01 EB000526NIBIB NIH HHS R01 EB007969
6 · The paper itself

Abstract

Retinal vein cannulation is a demanding procedure proposed to treat retinal vein occlusion by direct therapeutic agent delivery methods. Challenges in identifying the moment of venous puncture, achieving cannulation and maintaining cannulation during drug delivery currently limit the feasibility of the procedure. In this study, we respond to these problems with an assistive system combining a handheld micromanipulator, Micron, with a force-sensing microneedle. The integrated system senses the instant of vein puncture based on measured forces and the position of the needle tip. The system actively holds the cannulation device securely in the vein following cannulation and during drug delivery. Preliminary testing of the system in a dry phantom, stretched vinyl membranes, demonstrates a significant improvement in the total time the needle could be maintained stably inside of the vein. This was especially evident in smaller veins and is attributed to decreased movement of the positioned cannula following venous cannulation.

Identifiers

PMID27127804
PMCPMC4846290
OpenAlexW1949869788

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.