ArticleOxidative medicine and cellular longevity2016
Oxidative Stress in Children with Chronic Spontaneous Urticaria.
Article in Oxidative medicine and cellular longevity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 27 citations in OpenAlex.
- Identification of oxidative stress-related hub genes and immune infiltration characterization in chronic spontaneous urticaria.Molecular genetics and genomics : MGG · 2026Article
- Antioxidant, Antibacterial Properties of Novel Peptide CP by Enzymatic Hydrolysis ofMarine drugs · 2024Article
- The Role of Oxidative Stress in Atopic Dermatitis and Chronic Urticaria.Antioxidants (Basel, Switzerland) · 2022Article
- Thiol-Disulfide Homeostasis in Skin Diseases.Journal of clinical medicine · 2022Review
- Integrative lipidomic features identify plasma lipid signatures in chronic urticaria.Frontiers in immunology · 2022Article
- Does adiponectin play a role in the pathogenesis of chronic spontaneous urticaria?Central-European journal of immunology · 2020Article
- Stress, pseudoallergens, autoimmunity, infection and inflammation in chronic spontaneous urticaria.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019Review
- The Efficacy and Safety of a Fixed Combination of Chinese Herbal Medicine in Chronic Urticaria: A Randomized, Double-Blind, Placebo-Controlled Pilot Study.Frontiers in pharmacology · 2018Article
- Desloratadine Efficacy in Relation to GSTM1 and GSTT1 Polymorphic Genes in Chronic Spontaneous Urticaria.Indian journal of dermatologyArticle
- Evaluation of Thiol/Disulfide Homeostasis and İschemia-modified Albumin Levels in Symptomatic Dermographism.Indian journal of dermatologyArticle
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathogenesis of chronic spontaneous urticaria (CSU) has not been fully understood; nevertheless, significant progress has been achieved in recent years. The aim of this study was to investigate the possible role of reactive oxygen species (ROS) in the pathogenesis of CSU. Sixty-two children with CSU and 41 healthy control subjects were enrolled in the study. An extensive evaluation of demographic and clinical features was done, and serum oxidative stress was evaluated by plasma total oxidant status (TOS) and total antioxidant status (TAS) measurements. The median value of plasma TOS was found to be 10.49 μmol H2O2 equiv./L (interquartile range, 7.29-17.65) in CSU patients and 7.68 μmol H2O2 equiv./L (5.95-10.39) in the control group. The difference between the groups was statistically significant (p = 0.003). Likewise, the median plasma TAS level in the CSU group was decreased significantly compared to that of the control group (2.64 [2.30-2.74] versus 2.76 [2.65-2.86] mmol Trolox equiv./L, resp., p = 0,001). Our results indicated that plasma oxidative stress is increased in children with CSU when compared to healthy subjects, and plasma oxidative stress markers are positively correlated with disease activity.
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