Evidence map›Paper›PMID 27127306›Full record

ArticleInternational journal of heat and mass transfer2016

Long-range electrothermal fluid motion in microfluidic systems.

Yi Lu, Qinlong Ren, Tingting Liu, Siu Ling Leung, Vincent Gau, Joseph C Liao, Cho Lik Chan, Pak Kin Wong

Abstract read
In one paragraph

Article in International journal of heat and mass transfer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi LuDepartment of Aerospace and Mechanical Engineering, The University of Arizona, Tucson, Arizona, 85721, USA; Departments of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802 USA.
Qinlong RenDepartment of Aerospace and Mechanical Engineering, The University of Arizona, Tucson, Arizona, 85721, USA.
Tingting LiuDepartment of Aerospace and Mechanical Engineering, The University of Arizona, Tucson, Arizona, 85721, USA.
Siu Ling LeungDepartments of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802 USA; College of Medicine, The University of Arizona, Tucson, 85724, USA.
Vincent GauGeneFluidics Inc., Irwindale, California, 91010, USA.
Joseph C LiaoDepartment of Urology, Stanford University, Stanford, California, 94305, USA.
Cho Lik ChanDepartment of Aerospace and Mechanical Engineering, The University of Arizona, Tucson, Arizona, 85721, USA.
Pak Kin WongDepartment of Aerospace and Mechanical Engineering, The University of Arizona, Tucson, Arizona, 85721, USA; Departments of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802 USA; Departments of Mechanical and Nuclear Engineering, The Pennsylvania State University, University Park, PA 16802 USA; Department of Surgery, Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033 USA.

Funding

An Integrated Diagnostic System for Rapid Antimicrobial Susceptibility TestingR44AI088756 · NIAID · GENEFLUIDICS, INC. · PI GAU, VINCENT JEN-JR · 2012 to 2014
$3.0M
Mechanoregulation of Tissue MorphogenesisDP2OD007161 · OD · UNIVERSITY OF ARIZONA · PI WONG, PAK KIN · 2010 to 2010
$2.3M
NIAID NIH HHS R44 AI088756NIH HHS DP2 OD007161
6 · The paper itself

Abstract

AC electrothermal flow (ACEF) is the fluid motion created as a result of Joule heating induced temperature gradients. ACEF is capable of performing major microfluidic operations, such as pumping, mixing, concentration, separation and assay enhancement, and is effective in biological samples with a wide range of electrical conductivity. Here, we report long-range fluid motion induced by ACEF, which creates centimeter-scale vortices. The long-range fluid motion displays a strong voltage dependence and is suppressed in microchannels with a characteristic length below ~300 μm. An extended computational model of ACEF, which considers the effects of the density gradient and temperature-dependent parameters, is developed and compared experimentally by particle image velocimetry. The model captures the essence of ACEF in a wide range of channel dimensions and operating conditions. The combined experimental and computational study reveals the essential roles of buoyancy, temperature rise, and associated changes in material properties in the formation of the long-range fluid motion. Our results provide critical information for the design and modeling of ACEF based microfluidic systems toward various bioanalytical applications.

Indexed as

AC electrothermal flowbuoyancycomputational fluid dynamicselectrokineticsmicrofluidics

Identifiers

PMID27127306
PMCPMC4843167

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.