ReviewMaterials science & engineering. C, Materials for biological applications2016
Functional assessment of the ex vivo vocal folds through biomechanical testing: A review.
Review in Materials science & engineering. C, Materials for biological applications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Controlled-Release of Dexamethasone via Light-Activated Implant for Potential Vocal Fold Scar Treatment.ACS biomaterials science & engineering · 2025Article
- Drug delivery systems for wound healing treatment of upper airway injury.Expert opinion on drug delivery · 2024Review
- A self-fused hydrogel for the treatment of glottic insufficiency through outstanding durability, extracellular matrix-inducing bioactivity and function preservation.Bioactive materials · 2023Article
- Hydration State and Hyaluronidase Treatment Significantly Affect Porcine Vocal Fold Biomechanics.Journal of voice : official journal of the Voice Foundation · 2023Article
- Augmentation and vocal fold biomechanics in a recurrent laryngeal nerve injury model.Laryngoscope investigative otolaryngology · 2022Article
- Hydrogel-Supported, Engineered Model of Vocal Fold Epithelium.ACS biomaterials science & engineering · 2021Article
- The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening.Nature communications · 2021Article
- High-fidelity continuum modeling predicts avian voiced sound production.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Quantifying vocal fold wound-healing biomechanical property changes.The Laryngoscope · 2020Article
- Influence of vocal fold cover layer thickness on its vibratory dynamics during voice production.The Journal of the Acoustical Society of America · 2019Article
- Automated Indentation Mapping of Vocal Fold Structure and Cover Properties Across Species.The Laryngoscope · 2019Article
- Effect of Longitudinal Variation of Vocal Fold Inner Layer Thickness on Fluid-Structure Interaction During Voice Production.Journal of biomechanical engineering · 2018Article
- Viscoelastic properties of human aryepiglottic fold and ventricular fold tissues at phonatory frequencies.The Laryngoscope · 2018Article
- Impact of medialization laryngoplasty on dynamic nanomechanical vocal fold structure properties.The Laryngoscope · 2018Article
- Nonlinear viscoelastic characterization of human vocal fold tissues under large-amplitude oscillatory shear (LAOS).Journal of rheology · 2018Article
- Dynamic nanomechanical analysis of the vocal fold structure in excised larynges.The Laryngoscope · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The human vocal folds are complex structures made up of distinct layers that vary in cellular and extracellular composition. The mechanical properties of vocal fold tissue are fundamental to the study of both the acoustics and biomechanics of voice production. To date, quantitative methods have been applied to characterize the vocal fold tissue in both normal and pathologic conditions. This review describes, summarizes, and discusses the most commonly employed methods for vocal fold biomechanical testing. Force-elongation, torsional parallel plate rheometry, simple-shear parallel plate rheometry, linear skin rheometry, and indentation are the most frequently employed biomechanical tests for vocal fold tissues and each provide material properties data that can be used to compare native tissue to diseased or treated tissue. Force-elongation testing is clinically useful, as it allows for functional unit testing, while rheometry provides physiologically relevant shear data, and nanoindentation permits micrometer scale testing across different areas of the vocal fold as well as whole organ testing. Thoughtful selection of the testing technique during experimental design to evaluate a hypothesis is critical to optimize biomechanical testing of vocal fold tissues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.