ArticleJournal of magnetic resonance imaging : JMRI2016
Optimal combination of FLAIR and T2-weighted MRI for improved lesion contrast in multiple sclerosis.
Article in Journal of magnetic resonance imaging : JMRI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Cerebellar Roles in Motor and Social Functions and Implications for ASD.Cerebellum (London, England) · 2024Review
- Predicting Antiseizure Medication Treatment in Children with Rare Tuberous Sclerosis Complex-Related Epilepsy Using Deep Learning.AJNR. American journal of neuroradiology · 2023Article
- Recognizing Pediatric Tuberous Sclerosis Complex Based on Multi-Contrast MRI and Deep Weighted Fusion Network.Bioengineering (Basel, Switzerland) · 2023Article
- Sensitive Detection of Infratentorial and Upper Cervical Cord Lesions in Multiple Sclerosis with Combined 3D FLAIR and T2-Weighted (FLAIR3) Imaging.AJNR. American journal of neuroradiology · 2020Article
- The use of combined TRadiological physics and technology · 2019Article
- Interleaved susceptibility-weighted and FLAIR MRI for imaging lesion-penetrating veins in multiple sclerosis.Magnetic resonance in medicine · 2018Article
- Platform for Automated Real-Time High Performance Analytics on Medical Image Data.IEEE journal of biomedical and health informatics · 2018Article
- The Role of Advanced Magnetic Resonance Imaging Techniques in Multiple Sclerosis Clinical Trials.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2017Review
- Noise concerns and post-processing procedures in cerebral blood flow (CBF) and cerebral blood volume (CBV) functional magnetic resonance imaging.NeuroImage · 2017Review
- GRAPE: a graphical pipeline environment for image analysis in adaptive magnetic resonance imaging.International journal of computer assisted radiology and surgery · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposePostacquisition combination of three-dimensional T2-weighted (T2w) and fluid-attenuated inversion recovery (FLAIR) images can improve the visualization of brain lesions in multiple sclerosis (MS). However, an optimal way to combine these images has not been described so far. The main objective of this study is to investigate an optimal combination of T2w and FLAIR to improve the conspicuity of MS lesions. MATERIALS AND
methodsWe determined the parameters for a generalized multiplicative image combination which maximize the contrast-to-noise ratio (CNR) between lesions and normal-appearing brain tissue through simulations and verified experimentally. MRI data from 11 MS patients acquired at 3 Tesla were retrospectively analyzed using the proposed approach and compared with conventional FLAIR, and to images obtained by direct multiplication of T2w and FLAIR (FLAIR
resultsAn optimal combination was found to be the third order expression: FLAIR
conclusionThese results show that the optimized combination of FLAIR and T2w can improve MS lesion conspicuity. J. Magn. Reson. Imaging 2016;44:1293-1300.
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