ArticleJournal of experimental botany2016
Mitogen-activated protein kinase 4-like carrying an MEY motif instead of a TXY motif is involved in ozone tolerance and regulation of stomatal closure in tobacco.
Article in Journal of experimental botany, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Genome-wide screening of mitogen-activated protein kinase (MAPK) gene family and expression profile under heavy metal stress in Solanum lycopersicum.Biotechnology letters · 2025Article
- Harnessing the role of mitogen-activated protein kinases against abiotic stresses in plants.Frontiers in plant science · 2023Review
- Phytocyanin-encoding genes confer enhanced ozone tolerance in Arabidopsis thaliana.Scientific reports · 2022Article
- Genome-Wide Identification of MAPK, MAPKK, and MAPKKK Gene Families inFrontiers in genetics · 2022Article
- The Resistance of Oilseed Rape Microspore-Derived Embryos to Osmotic Stress Is Associated With the Accumulation of Energy Metabolism Proteins, Redox Homeostasis, Higher Abscisic Acid, and Cytokinin Contents.Frontiers in plant science · 2021Article
- The Pepper Mitogen-Activated Protein Kinase CaMAPK7 Acts as a Positive Regulator in Response toFrontiers in microbiology · 2021Article
- Receptor-Like Protein Kinases Function Upstream of MAPKs in Regulating Plant Development.International journal of molecular sciences · 2020Review
- Article
- The Function of MAPK Cascades in Response to Various Stresses in Horticultural Plants.Frontiers in plant science · 2020Review
- Overexpression of a Mitogen-Activated Protein KinaseMolecules (Basel, Switzerland) · 2019Article
- Mitogen-activated protein kinases MPK4 and MPK12 are key components mediating COThe Plant journal : for cell and molecular biology · 2018Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mitogen-activated protein kinases (MAPKs/MPKs) are important factors in the regulation of signal transduction in response to biotic and abiotic stresses. Previously, we characterized a MAPK from tobacco, Nicotiana tabacum MPK4 (NtMPK4). Here, we found a highly homologous gene, NtMPK4-like (NtMPK4L), in tobacco as well as other species in Solanaceae and Gramineae. Deduced amino acid sequences of their translation products carried MEY motifs instead of conserved TXY motifs of the MAPK family. We isolated the full length NtMPK4L gene and examined the physiological functions of NtMPK4L. We revealed that NtMPK4L was activated by wounding, like NtMPK4. However, a constitutively active salicylic acid-induced protein kinase kinase (SIPKK(EE)), which phosphorylates NtMPK4, did not phosphorylate NtMPK4L. Moreover, a tyrosine residue in the MEY motif was not involved in NtMPK4L activation. We also found that NtMPK4L-silenced plants showed rapid transpiration caused by remarkably open stomata. In addition, NtMPK4L-silenced plants completely lost the ability to close stomata upon ozone treatment and were highly sensitive to ozone, suggesting that this atypical MAPK plays a role in ozone tolerance through stomatal regulation.
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