Evidence map›Paper›PMID 27126154›Full record

Trial reportJournal of the Academy of Nutrition and Dietetics2016

Elevated Serum Osmolality and Total Water Deficit Indicate Impaired Hydration Status in Residents of Long-Term Care Facilities Regardless of Low or High Body Mass Index.

Melissa Ventura Marra, Sandra F Simmons, Matthew S Shotwell, Abbie Hudson, Emily K Hollingsworth, Emily Long, Brittany Kuertz, Heidi J Silver

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of the Academy of Nutrition and Dietetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

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  12. Microbiota-Liver Diseases Interactions.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Melissa Ventura Marra
Sandra F Simmons
Matthew S Shotwell
Abbie Hudson
Emily K Hollingsworth
Emily Long
Brittany Kuertz
Heidi J Silver

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR) KL2KL2RR024977 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$3.0M
Cost-Effectiveness of Weight Loss Prevention in Nursing Homes: A Controlled TrialR01HS018580 · AHRQ · VANDERBILT UNIVERSITY · PI SIMMONS, SANDRA F · 2009 to 2012
$2.0M
Cost-Effectiveness of Two Nutrition Interventions in Long-Term CareR01AG033828 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SIMMONS, SANDRA F · 2011 to 2014
$1.6M
AHRQ HHS R01 HS018580NCRR NIH HHS KL2 RR024977NCRR NIH HHS UL 1 RR024975-01NIA NIH HHS R01 AG033828
6 · The paper itself

Abstract

backgroundDehydration is typically associated with underweight and malnutrition in long-term care (LTC) settings. Evidence is lacking regarding the influence of the rising prevalence of overweight and obesity on risk factors, prevalence, and presentation of dehydration.

objectiveThe aim of this study was to objectively assess hydration status and the adequacy of total water intake, and determine relationships between hydration status, total water intake, and body mass index (BMI) in LTC residents.

designA cross-sectional analysis of baseline data was performed. PARTICIPANTS AND

settingBaseline data from 247 subjects recruited from eight community-based LTC facilities participating in two randomized trials comparing nutrient and cost-efficacy of between-meal snacks vs oral nutrition supplements (ONS). MAIN OUTCOMES: Hydration status was assessed by serum osmolality concentration and total water intakes were quantified by weighed food, beverage, water, and ONS intake. STATISTICAL ANALYSES: Simple and multiple linear regression methods were applied.

resultsForty-nine (38.3%) subjects were dehydrated (>300 mOsm/kg) and another 39 (30.5%) had impending dehydration (295 to 300 mOsm/kg). The variance in serum osmolality was significantly accounted for by blood urea nitrogen level, mental status score, and having diabetes (R(2)=0.46; P<0.001). Total water intake averaged 1,147.2±433.1 mL/day. Thus, 96% to 100% of subjects did not meet estimated requirements, with a deficit range of 700 to 1,800 mL/day. The variance in total water intake was significantly accounted for by type of liquid beverages (thin vs thick), type of ONS, total energy intake, total activities of daily living dependence, sex, and BMI (R(2)=0.56; P<0.001).

conclusionsDehydration and inadequate total water intake is prevalent in LTC residents across all BMI categories. Type of liquid beverages, type of ONS, and type of between-meal snacks are factors that could be targeted for nutrition interventions designed to prevent or reverse dehydration.

Indexed as

Body Mass IndexLong-Term CareActivities of Daily LivingAgedAged, 80 and overBeveragesBiomarkersBlood Urea NitrogenBody WeightCost-Benefit AnalysisCreatinineCross-Sectional StudiesDehydrationDrinkingEnergy IntakeFemaleBiomarkersCreatinineElderlyFluidHydrationLong-term careOlder adult

Identifiers

PMID27126154
PMCPMC4852282
OpenAlexW2344557663

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.