Evidence map›Paper›PMID 27126091›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2016

Identification of bona-fide LRRK2 kinase substrates.

Andrew B West, Mark R Cookson

Abstract readEditorialComment
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Andrew B WestCenter for Neurodegeneration and Experimental Therapeutics, Department of Neurology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Mark R CooksonCell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.

Funding

Leucine rich repeat kinase 2 and dominantly inherited Parkinson diseaseZIAAG000948 · NIA · NATIONAL INSTITUTE ON AGING · PI COOKSON, MARK · 2009 to 2025
$18.3M
Mechanisms of LRRK2 Mediated NeurotoxicityR01NS064934 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WEST, ANDREW B · 2010 to 2025
$6.3M
Exosome LRRK2 in Predicting Parkinson Disease PhenotypesU01NS097028 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WEST, ANDREW B · 2016 to 2018
$1.0M
LRRK2 and Other Novel Exosome Proteins in Parkinson's DiseaseU18NS082132 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WEST, ANDREW B · 2012 to 2015
$934k
Validation of the JAK/STAT Signaling Pathway in PDP20NS092530 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STANDAERT, DAVID G. · 2015 to 2016
$642k
Medical Research Council MC_UU_12016/3NINDS NIH HHS P20 NS092530NINDS NIH HHS R01 NS064934NINDS NIH HHS U01 NS097028NINDS NIH HHS U18 NS082132
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leucine-Rich Repeat Serine-Threonine Protein Kinase-2Protein Serine-Threonine KinasesParkinson DiseaseLeucine-Rich Repeat Serine-Threonine Protein Kinase-2Protein Serine-Threonine Kinases

Identifiers

PMID27126091
PMCPMC4981516

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.