Evidence map›Paper›PMID 27126063›Full record

ArticleJournal of medical systems2016

Multiple Imputation based Clustering Validation (MIV) for Big Longitudinal Trial Data with Missing Values in eHealth.

Zhaoyang Zhang, Hua Fang, Honggang Wang

Abstract readValidation Study
In one paragraph

Article in Journal of medical systems, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Feature Interaction Detection in Big Data Through a New Choquet Integral based Deep Neural Network.Proceedings : ... IEEE International Conference on Big Data. IEEE International Conference on Big Data · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. eFCM: An Enhanced Fuzzy C-Means Algorithm for Longitudinal Intervention Data.International Conference on Computing, Networking, and Communications : [proceedings]. International Conference on Computing, Networking and Communications · 2018
    Article
  10. Article
  11. Article
  12. Review
  13. Multiple- vs Non- or Single-Imputation based Fuzzy Clustering for Incomplete Longitudinal Behavioral Intervention Data....IEEE...International Conference on Connected Health: Applications, Systems and Engineering Technologies. IEEE International Conference on Connected Health: Applications, Systems and Engineering Technologies · 2016
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhaoyang ZhangDepartment of Quantitative Health Science, University of Massachusetts Medical School, Worcester, MA, 01655, USA.
Hua FangDepartment of Quantitative Health Science, University of Massachusetts Medical School, Worcester, MA, 01655, USA. hua.fang@umassmed.edu.
Honggang WangDepartment of Electrical and Computer Engineering, University of Massachusetts Dartmouth, North Dartmouth, MA, 02747, USA.

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
UNIVERSITY OF MASSACHUSETTS CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCEUL1RR031982 · NCRR · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SULLIVAN, JOHN LEWIS · 2010 to 2011
$6.8M
DISC: Describe Smoking Cessation in RCT Multi-Component Behavioral InterventionR01DA033323 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FANG, HUA · 2013 to 2015
$701k
NCATS NIH HHS UL1 TR001453NCRR NIH HHS 1UL1RR031982-01NCRR NIH HHS UL1 RR031982NIDA NIH HHS R01 DA033323
6 · The paper itself

Abstract

Web-delivered trials are an important component in eHealth services. These trials, mostly behavior-based, generate big heterogeneous data that are longitudinal, high dimensional with missing values. Unsupervised learning methods have been widely applied in this area, however, validating the optimal number of clusters has been challenging. Built upon our multiple imputation (MI) based fuzzy clustering, MIfuzzy, we proposed a new multiple imputation based validation (MIV) framework and corresponding MIV algorithms for clustering big longitudinal eHealth data with missing values, more generally for fuzzy-logic based clustering methods. Specifically, we detect the optimal number of clusters by auto-searching and -synthesizing a suite of MI-based validation methods and indices, including conventional (bootstrap or cross-validation based) and emerging (modularity-based) validation indices for general clustering methods as well as the specific one (Xie and Beni) for fuzzy clustering. The MIV performance was demonstrated on a big longitudinal dataset from a real web-delivered trial and using simulation. The results indicate MI-based Xie and Beni index for fuzzy-clustering are more appropriate for detecting the optimal number of clusters for such complex data. The MIV concept and algorithms could be easily adapted to different types of clustering that could process big incomplete longitudinal trial data in eHealth services.

Indexed as

Cluster AnalysisLongitudinal StudiesTelemedicineAlgorithmsClinical Trials as TopicData Interpretation, StatisticalFuzzy LogicHumansBig dataFuzzy clusteringLongitudinal trialMissing dataMultiple imputationValidation

Identifiers

PMID27126063
PMCPMC4881752

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.