Evidence map›Paper›PMID 27125677›Full record

ReviewCurrent opinion in cell biology2016

Acidocalcisomes of eukaryotes.

Roberto Docampo, Guozhong Huang

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Euglena gracilis Subcellular Fractionation.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Failure ofInternational journal of molecular sciences · 2023
    Article
  13. A spatially resolved elemental nanodomain organization within acidocalcisomes inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Article
  15. Article
  16. New insights into the role of acidocalcisomes in trypanosomatids.The Journal of eukaryotic microbiology · 2022
    Review
  17. Review
  18. Article
  19. Article
  20. A new subspecies ofParasitology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Roberto DocampoCenter for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA. Electronic address: rdocampo@cb.uga.edu.
Guozhong HuangCenter for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA.
University of Georgia · US

Funding

The roles of polyphosphate and acidocalcisomes in Trypanosoma bruceiR01AI077538 · NIAID · UNIVERSITY OF GEORGIA · PI DOCAMPO, ROBERTO · 2009 to 2019
$3.8M
Calcium signaling in Trypanosoma bruceiR01AI108222 · NIAID · UNIVERSITY OF GEORGIA · PI DOCAMPO, ROBERTO · 2014 to 2017
$1.5M
NIAID NIH HHS R01 AI077538NIAID NIH HHS R01 AI108222
6 · The paper itself

Abstract

Acidocalcisomes are organelles rich in polyphosphate and cations and acidified by proton pumps. Although they have also been described in prokaryotes they have been better characterized in unicellular and multicellular eukaryotes. Eukaryotic acidocalcisomes belong to the group of lysosome-related organelles. They have a variety of functions, from the storage of cations and phosphorus to calcium signaling, autophagy, osmoregulation, blood coagulation, and inflammation. Acidocalcisomes of several unicellular eukaryotes possess a variety of transporters, channels and pumps implying a large energetic requirement for their maintenance and suggesting other important functions waiting to be discovered.

Indexed as

AcidsAnimalsCalciumEukaryotaHumansOrganellesOvumPolyphosphatesAcidsCalciumPolyphosphates

Identifiers

PMID27125677
PMCPMC4983533
OpenAlexW2345219027

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.