Evidence map›Paper›PMID 27124947›Full record

ReviewAmerican journal of clinical pathology2016

Pathology Consultation on Influenza Diagnostics.

Allison R McMullen, Neil W Anderson, Carey-Ann D Burnham, Education Committee of the Academy of Clinical Laboratory Physicians and Scientists

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of clinical pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Detection and Prevention of Virus Infection.Advances in experimental medicine and biology · 2022
    Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Allison R McMullenFrom the Department of Pathology and Immunology, Washington University in St Louis School of Medicine, St Louis, MO.
Neil W AndersonFrom the Department of Pathology and Immunology, Washington University in St Louis School of Medicine, St Louis, MO.
Carey-Ann D BurnhamFrom the Department of Pathology and Immunology, Washington University in St Louis School of Medicine, St Louis, MO. cburnham@path.wustl.edu.
Education Committee of the Academy of Clinical Laboratory Physicians and Scientists
Washington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the strengths and limitations of the available influenza diagnostics, with a focus on rapid antigen detection assays and nucleic acid detection assays.

methodsA case-based presentation is used to illustrate the potential limitations of rapid antigen detection assays for influenza.

resultsInfluenza is a seasonal illness; estimates attribute influenza to approximately 200,000 hospitalizations and 41,000 deaths in the United States annually. Antigen detection assays for influenza are rapid and convenient, and thus are widely used in a variety of health care settings, even though the sensitivity of these assays may be suboptimal. The United States Food and Drug Administration has recently created new guidelines intended to improve the oversight and performance characteristics of influenza antigen detection assays. Molecular assays, although more costly and complex, are more sensitive and may be designed to simultaneously detect multiple respiratory pathogens within a single assay.

conclusionsDiagnostic assays for influenza can vary greatly with regards to analytical performance characteristics, complexity, turnaround time and cost. This can have important patient care and infection prevention implications.

Indexed as

HumansInfluenza, HumanMolecular Diagnostic TechniquesPathology, ClinicalReferral and ConsultationDiagnosticsInfluenzaNucleic acid amplification testsRapid influenza diagnostic testRespiratory virus

Identifiers

PMID27124947
PMCPMC7110119
OpenAlexW2345104590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.