Evidence map›Paper›PMID 27124297›Full record

ArticlePloS one2016

The Minimal Important Difference in Physical Activity in Patients with COPD.

Heleen Demeyer, Chris Burtin, Miek Hornikx, Carlos Augusto Camillo, Hans Van Remoortel, Daniel Langer, Wim Janssens, Thierry Troosters

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 148 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
148citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06165978 nasuspendednot on this mapstarted 2024, after this paper: background citation

Physical Activity Coaching in Patients with Post-COVID-19. a Randomised Clinical Trial.

TypeinterventionalSponsorUniversity of AlcalaRan2024 to 2027Enrolled162ConditionsPost-COVID-19 SyndromeArmsSelf-monitoring, Goal setting and review, Education, Feedback, Contact
NCT06732869 narecruitingnot on this mapstarted 2024, after this paper: background citation

PACE - Physical Activity in COPD Using E-Health: Effectiveness of a Personalised eHealth Platform Integrated Into Pulmonary Rehabilitation to Increase Physical Activity in Patients With COPD - a Randomized Controlled Trial

TypeinterventionalSponsorInstituto Politécnico de LeiriaRan2024 to 2025Enrolled57ConditionsCOPD, Physical ActivityArmseHealth physical activity coaching intervention, pulmonary rehabilitation
3 · Its place in the literature

Who cites it

148 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  6. Physical activity promotion interventions in chronic airways disease: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
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  7. Impact of Seasonality on Physical Activity: A Systematic Review.International journal of environmental research and public health · 2021
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  10. Use of pedometers as a tool to promote daily physical activity levels in patients with COPD: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2019
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88 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Heleen DemeyerKU Leuven-University of Leuven, Department of Rehabilitation Sciences, B-3000 Leuven, Belgium.
Chris BurtinKU Leuven-University of Leuven, Department of Rehabilitation Sciences, B-3000 Leuven, Belgium.
Miek HornikxKU Leuven-University of Leuven, Department of Rehabilitation Sciences, B-3000 Leuven, Belgium.
Carlos Augusto CamilloKU Leuven-University of Leuven, Department of Rehabilitation Sciences, B-3000 Leuven, Belgium.
Hans Van RemoortelKU Leuven-University of Leuven, Department of Rehabilitation Sciences, B-3000 Leuven, Belgium.
Daniel LangerKU Leuven-University of Leuven, Department of Rehabilitation Sciences, B-3000 Leuven, Belgium.
Wim JanssensUniversity Hospitals Leuven, Department of Respiratory Diseases, B-3000 Leuven, Belgium.
Thierry TroostersKU Leuven-University of Leuven, Department of Rehabilitation Sciences, B-3000 Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChanges in physical activity (PA) are difficult to interpret because no framework of minimal important difference (MID) exists. We aimed to determine the minimal important difference (MID) in physical activity (PA) in patients with Chronic Obstructive Pulmonary Disease and to clinically validate this MID by evaluating its impact on time to first COPD-related hospitalization.

methodsPA was objectively measured for one week in 74 patients before and after three months of rehabilitation (rehabilitation sample). In addition the intraclass correlation coefficient was measured in 30 patients (test-retest sample), by measuring PA for two consecutive weeks. Daily number of steps was chosen as outcome measurement. Different distribution and anchor based methods were chosen to calculate the MID. Time to first hospitalization due to an exacerbation was compared between patients exceeding the MID and those who did not.

resultsCalculation of the MID resulted in 599 (Standard Error of Measurement), 1029 (empirical rule effect size), 1072 (Cohen's effect size) and 1131 (0.5SD) steps.day-1. An anchor based estimation could not be obtained because of the lack of a sufficiently related anchor. The time to the first hospital admission was significantly different between patients exceeding the MID and patients who did not, using the Standard Error of Measurement as cutoff.

conclusionsThe MID after pulmonary rehabilitation lies between 600 and 1100 steps.day-1. The clinical importance of this change is supported by a reduced risk for hospital admission in those patients with more than 600 steps improvement.

Indexed as

Outcome Assessment, Health CareAgedExerciseExercise TestExercise ToleranceFemaleHospitalizationHumansMalePulmonary Disease, Chronic ObstructiveRetrospective StudiesSurveys and Questionnaires

Identifiers

PMID27124297
PMCPMC4849755

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.