ReviewScientifica2016
Onychomycosis: Potential of Nail Lacquers in Transungual Delivery of Antifungals.
Review in Scientifica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- The use of urea for the treatment of onychomycosis: a systematic review.Journal of foot and ankle research · 2019Pooled it
- Nanocarriers in Ungual Drug Delivery.Pharmaceutics · 2025Review
- Nail Polishes: A Review on Composition, Presence of Toxic Components, and Inadequate Labeling.Dermatology research and practice · 2025Review
- Novel Therapeutic Approaches Emerging in the Field of Onychomycosis.Recent advances in anti-infective drug discovery · 2025Review
- Determining the efficacy of phytoconstituents ofIn silico pharmacology · 2025Article
- Nanoformulations Insights: A Novel Paradigm for Antifungal Therapies and Future Perspectives.Current drug delivery · 2024Review
- Design, Development, and Evaluation of Constant Voltage Iontophoresis for the Transungual Delivery of Efinaconazole.Pharmaceutics · 2023Article
- Effect of the 1064 nm Nd: YAG Laser on the MICs of Antifungals Used in Clinical Practice for the Treatment of Fungal Nail Infections.Journal of lasers in medical sciences · 2023Article
- In Silico Drug Screening Based Development of Novel Formulations for Onychomycosis Management.Gels (Basel, Switzerland) · 2021Article
- Application of central composite design for the optimization of itraconazole loaded nail lacquer formulation.3 Biotech · 2021Article
- Potential of Naftifine Application for Transungual Delivery.Molecules (Basel, Switzerland) · 2020Article
- Onychomycosis: An Updated Review.Recent patents on inflammation & allergy drug discovery · 2020Review
- Molecular Docking-Guided Ungual Drug-Delivery Design for Amelioration of Onychomycosis.ACS omega · 2019Article
- Potential of Chemical and Physical Enhancers for Transungual Delivery of Amorolfine Hydrochloride.Materials (Basel, Switzerland) · 2019Article
- Recent Patents on Permeation Enhancers for Drug Delivery Through Nails.Recent patents on drug delivery & formulation · 2019Review
- Novel Drug Delivery Strategies for the Treatment of Onychomycosis.Pharmaceutical nanotechnology · 2019Review
- Effect on Nail Structure and Transungual Permeability of the Ethanol and Poloxamer Ratio from Cyclodextrin-Soluble Polypseudorotaxanes Based Nail Lacquer.Pharmaceutics · 2018Article
- Propolis Extract for Onychomycosis Topical Treatment: From Bench to Clinic.Frontiers in microbiology · 2018Article
- Role of Polyethylene Glycol in Dermatology.Indian dermatology online journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Onychomycosis constitutes the most common fungal infection of the nail (skin beneath the nail bed) that affects the finger as well as toe nails. It is an infection that is initiated by yeasts, dermatophytes, and nondermatophyte molds. Nail lacquers are topical solutions intended only for use on fingernails as well as toenails and have been found to be useful in the treatment of onychomycosis. Thus, in the present review an attempt has been made to focus on the treatment aspects of onychomycosis and the ungual delivery of antifungals via nail lacquer. Several patents issued on nail lacquer till date have also been discussed. Penetration efficiency was assessed by several researchers across the human nail plate to investigate the potentiality of nail lacquer based formulations. Various clinical trials have also been conducted in order to evaluate the safety and efficacy of nail lacquers in delivering antifungal agents. Thus, it can be concluded that nail lacquer based preparations are efficacious and stable formulations. These possess tremendous potential for clinical topical application to the nail bed in the treatment of onychomycosis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.