ArticleMolecular and clinical oncology2016
Response to chemotherapy with carboplatin plus albumin-bound paclitaxel in a patient with lymphoepithelioma-like thymic carcinoma: A case report.
Article in Molecular and clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Carboplatin plus nanoparticle albumin-bound paclitaxel for the treatment of thymic carcinoma.Molecular and clinical oncology · 2022Article
- Thymic Lymphoepithelial Carcinoma Associated with Epstein-Barr Virus: Experiences and Literature Review.Cancers · 2021Review
- Total thymectomy for thymic lymphoepithelioma-like carcinoma-report of two cases.Surgical case reports · 2019Article
- Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors.OncoTargets and therapy · 2017Review
- First-Line Treatment with Carboplatin plusCase reports in oncologyArticle
- Successful Treatment of Advanced Thymic Carcinoma with Carboplatin plusCase reports in oncologyArticle
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
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Abstract
Thymic carcinoma is a rare neoplasm with a poor outcome due to its aggressive characteristics. For patients who are not operable, radiation therapy and/or palliative chemotherapy are indicated. However, no optimal chemotherapy regimen has been established. The present study reports the case of a 22-year-old man with advanced lymphoepithelioma-like thymic carcinoma refractory to conventional chemotherapy with carboplatin plus solvent-based paclitaxel (sb-PAC) treatment. The patient was subsequently treated with carboplatin plus nanoparticle albumin-bound paclitaxel (nab-PAC). The treatment resulted in a partial response following three cycles of chemotherapy. Since only grade 3 neutropenia, but no other severe adverse effects, was observed, no dose reduction was required. To the best of our knowledge, the current study is the first to present the response to chemotherapy with carboplatin plus nab-PAC in a patient with lymphoepithelioma-like thymic carcinoma. Considering that no standard treatment has been established in thymic carcinoma, nab-PAC may merit further investigation in this rare, but aggressive disease.
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