Evidence map›Paper›PMID 27123244›Full record

ArticleBiomedical reports2016

Role of exercise in the treatment of alcohol use disorders.

Eirini Manthou, Kalliopi Georgakouli, Ioannis G Fatouros, Christina Gianoulakis, Yannis Theodorakis, Athanasios Z Jamurtas

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
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  9. Mental health and physical activity · 2024
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  17. A novel theory on the predictive value of variation in the β-endorphin system on the risk and severity of PTSD.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Eirini ManthouDepartment of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece; Department of Kinesiology, Institute for Research and Technology Thessaly, 42100 Trikala, Greece.
Kalliopi GeorgakouliDepartment of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece; Department of Kinesiology, Institute for Research and Technology Thessaly, 42100 Trikala, Greece.
Ioannis G FatourosDepartment of Kinesiology, Institute for Research and Technology Thessaly, 42100 Trikala, Greece.
Christina GianoulakisMcGill University and Douglas Mental Health University Institute, Montreal, Quebec H4H 1R3, Canada.
Yannis TheodorakisDepartment of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece.
Athanasios Z JamurtasDepartment of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece; Department of Kinesiology, Institute for Research and Technology Thessaly, 42100 Trikala, Greece.
University of Thessaly · GRCenter for Research and Technology Thessaly · GRMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive alcohol use can cause harmful effects on the human body, which are associated with serious health problems, and it can also lead to the development of alcohol use disorders (AUDs). There is certain evidence that physical exercise positively affects excessive alcohol use and the associated problems by leading to reduced alcohol intake. A literature search was conducted using the databases PubMed, Medline and Web of Science. The search terms used as keywords were: Addiction, abuse, alcohol use disorders, exercise training, β-endorphin, opioids, brain, ethanol and alcohol. The current study presents the studies that reported on the use of exercise in the treatment of AUDs between 1970 and 2015. The potential psychological and physiological mechanisms that contribute to the action of exercise were also reviewed, highlighting the role of β-endorphin and the hypothalamic-pituitary-adrenal axis in AUDs and the possible association among physical activity, the endogenous opioid system and the desire for alcohol. Only 11 studies were identified that refer to the effect of exercise on alcohol consumption and/or the associated outcomes. Six of those studies concluded that exercise may have a positive impact towards alcohol consumption, abstinence rates or the urge to drink. One of those studies also indicated that a bout of exercise affects the endogenous opioids, which may be associated with the urge to drink. Another 3 studies indicated that responses to acute exercise in individuals with AUDs are different compared to those in healthy ones. Generally, despite limited research data and often contradictory results, there is certain early promising evidence for the role of exercise as an adjunctive tool in the treatment of AUDs. Physiological and biochemical parameters that would confirm that exercise is safe for individuals with AUDs should be examined in future studies.

Indexed as

alcoholismbrainethanolexercise trainingopioidsβ-endorphin

Identifiers

PMID27123244
PMCPMC4840498
OpenAlexW2293383197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.