Evidence map›Paper›PMID 27123182›Full record

ArticleJournal of market access & health policy2015

The intangible benefits of vaccination - what is the true economic value of vaccination?

Paolo Bonanni, Juan José Picazo, Vanessa Rémy

Open access · goldAbstract read
In one paragraph

Article in Journal of market access & health policy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  9. Review
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  12. 2. How is the economic assessment of vaccines performed today?Journal of market access & health policy · 2017
    Review
  13. Article
  14. Role of vaccination in economic growth.Journal of market access & health policy · 2015
    Article
  15. The Economic Value of Vaccination: Why Prevention is Wealth.Journal of market access & health policy · 2015
    Article
  16. Role of vaccination in the sustainability of healthcare systems.Journal of market access & health policy · 2015
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Paolo BonanniDepartment of Health Sciences, University of Florence, Florence, Italy.
Juan José PicazoDepartment of Clinical Microbiology, Hospital Clinico San Carlos, Madrid, Spain.
Vanessa RémySanofi Pasteur MSD, Lyon, France.
Hospital Clínico San Carlos · ESSanofi (France) · FRUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous economic evaluations of new vaccines largely focussed on a narrow set of benefit categories, including primarily health gains and disease-related medical cost-savings, which probably resulted in underestimates of the true value of these vaccines. Other economic benefits of vaccines could be considered to assess the full economic value of vaccination, such as, for example, impact of the human papillomavirus vaccine on women's fertility through the decrease in precancerous lesions and, therefore, in the number of diagnostic and treatment interventions, which can be associated with an increased risk of subsequent pregnancy complications. Vaccines' impact on resource allocation at hospital level or on antimicrobial resistance, such as pneumococcal conjugate vaccines that have substantially reduced infections due to antimicrobial non-susceptible strains, thereby rendering the residual disease easier to treat, are other examples of intangible benefits of vaccination. These benefits are generally not considered in economic evaluations because they may not be immediately visible and are difficult to quantify. However, they should be taken into consideration in health technology assessments to enable those responsible for healthcare policies to make well-informed decisions on vaccination.

Indexed as

antibiotic resistancecomplicationseconomic evaluationhealthcare systemintangible benefitsvaccination

Identifiers

PMID27123182
PMCPMC4802696
OpenAlexW1900735711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.