Evidence map›Paper›PMID 27123052›Full record

ArticleOncology letters2016

Prognostic significance of claudin-1 and cyclin B1 protein expression in patients with hypopharyngeal squamous cell carcinoma.

Wujie Li, Qing Dong, Lei Li, Zhenlei Zhang, Xiaolan Cai, Xinliang Pan

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Claudin-1, A Double-Edged Sword in Cancer.International journal of molecular sciences · 2020
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Polymorphisms ofJournal of Cancer · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wujie LiDepartment of Otolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China; Department of Otolaryngology, Tai'an City Central Hospital, Tai'an, Shandong 271000, P.R. China.
Qing DongDepartment of Pediatrics, Tai'an City Central Hospital, Tai'an, Shandong 271000, P.R. China.
Lei LiDepartment of Gastroenterology, Tai'an City Central Hospital, Tai'an, Shandong 271000, P.R. China.
Zhenlei ZhangDepartment of Otolaryngology, Tai'an City Central Hospital, Tai'an, Shandong 271000, P.R. China.
Xiaolan CaiDepartment of Otolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Xinliang PanDepartment of Otolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Qilu Hospital of Shandong University · CNTaian City Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Claudin-l and cyclin B1 are abnormally expressed in certain malignancies, but their expression in hypopharyngeal squamous cell carcinoma (HSCC) has not been reported thus far. Studying the expression levels of claudin-1 and cylin B1 in HSCC tissues and their association with clinical stage, pathological grade and prognosis in patients with HSCC may provide a theoretical basis and guide future research on HSCC targeted therapy. The protein expression levels of the above two biomarkers was immunohistochemically detected in 97 HSCC cases and 90 matched adjacent tissue samples. The correlation between the expression levels of claudin-1 and cylin B1 and the patients' clinical parameters was analyzed via Pearson's χ

Indexed as

claudin-1cyclin B1hypopharyngeal squamous cell carcinomaimmunohistochemical

Identifiers

PMID27123052
PMCPMC4840523
OpenAlexW2300992720

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.