Evidence map›Paper›PMID 27122974›Full record

ArticleCurrent oncology (Toronto, Ont.)2016

Canadian recommendations for the management of breakthrough cancer pain.

P Daeninck, B Gagnon, R Gallagher, J D Henderson, Y Shir, C Zimmermann, B Lapointe

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Multidimensional Treatment of Cancer Pain.Current oncology reports · 2017
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Breakthrough cancer pain: review and calls to action to improve its management.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Practical Pharmacology of Methadone: A Long-acting Opioid.Indian journal of palliative care · 2018
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 2 countries.

P DaeninckUniversity of Manitoba, Winnipeg, MB;
B GagnonDepartment of Family Medicine and Emergency Medicine, Laval University, Quebec City, QC;
R GallagherUniversity of British Columbia, Vancouver, BC, and Division of Palliative Care, Providence Health Care, Toronto, ON;
J D HendersonColchester East Hants Palliative Care Program, Truro, and Atlantic Palliative Medicine Group and Dalhousie University, Halifax, NS;
Y ShirAlan Edwards Pain Management Unit, McGill University, Montreal, QC;
C ZimmermannPalliative Services, University Health Network, University of Toronto, Toronto, ON;
B LapointeMcGill University, Montreal, QC.
Dalhousie University · CAEdwards (United Kingdom) · GBMcGill University · CAProvidence Health Care · CAUniversité Laval · CAUniversity Health Network · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breakthrough cancer pain (btcp) represents an important element in the spectrum of cancer pain management. Because most btcp episodes peak in intensity within a few minutes, speed of medication onset is crucial for proper control. In Canada, several current provincial guidelines for the management of cancer pain include a brief discussion about the treatment of btcp; however, there are no uniform national recommendations for the management of btcp. That lack, accompanied by unequal access to pain medication across the country, contributes to both regional and provincial variability in the management of btcp. Currently, immediate-release oral opioids are the treatment of choice for btcp. This approach might not always offer optimal speed for onset of action and duration to match the rapid nature of an episode of btcp. Novel transmucosal fentanyl formulations might be more appropriate for some types of btcp, but limited access to such drugs hinders their use. In addition, the recognition of btcp and its proper assessment, which are crucial steps toward appropriate treatment selection, remain challenging for many health care professionals. To facilitate appropriate management of btcp, a group of prominent Canadian specialists in palliative care, oncology, and anesthesiology convened to develop a set of recommendations and suggestions to assist Canadian health care providers in the treatment of btcp and the alleviation of the suffering and discomfort experienced by adult cancer patients.

Indexed as

Breakthrough cancer pain

Identifiers

PMID27122974
PMCPMC4835001
OpenAlexW2336469532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.