ArticleActa Cardiologica Sinica2015
Clinical Profile and Long-Term Prognostic Factors of a Young Chinese Han Population (≤ 40 Years) Having ST-Segment Elevation Myocardial Infarction.
Article in Acta Cardiologica Sinica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Effect of factor XIII levels and polymorphisms on the risk of myocardial infarction in young patients.Molecular and cellular biochemistry · 2018Trial
- Current status of premature myocardial infarction research in China: a systematic review and international comparative perspective.Frontiers in cardiovascular medicine · 2026Review
- Evaluating Long-Term Outcomes in STEMI Patients with New Left Bundle Branch Block: The Impact of Modifiable Risk Factors.Journal of personalized medicine · 2024Article
- Clinical risk factors and outcomes of young patients with acute ST segment elevation myocardial infarction: a retrospective study.BMC cardiovascular disorders · 2023Article
- Risk Factors for Premature Myocardial Infarction: A Systematic Review and Meta-analysis of 77 Studies.Mayo Clinic proceedings. Innovations, quality & outcomes · 2021Article
- Clinical Characteristics, Prognosis, and Gender Disparities in Young Patients With Acute Myocardial Infarction.Frontiers in cardiovascular medicine · 2021Article
- Clinical, Demographic, and Biochemical Characteristics of Patients with Acute ST-Segment Elevation Myocardial Infarction: An Analysis of Acute Coronary Syndrome Registry Data of a Single Medical Center from 2005 to 2016.Acta Cardiologica Sinica · 2020Article
- Article
- Clinical Characteristics of Patients Less than Forty Years Old with Coronary Artery Disease in Taiwan: A Cross-Sectional Study.Acta Cardiologica Sinica · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe proportion of the mainland Chinese population with premature ST-segment elevation myocardial infarction is significantly elevated. Young patients with ST-segment elevation myocardial infarction have a different risk factor profile and clinical outcome compared with elder patients, and may also differ as compared to young patients in Western populations.
methodsWe analyzed a total of 9462 consecutive ST-segment elevation myocardial infarction patients, and recruited 341 consecutive cases who had survived their first ST-segment elevation myocardial infarction at the age less than 40 years, and followed-up these patients for 5 years.
resultsThe most prevalent risk factor in young Chinese ST-segment elevation myocardial infarction patients was smoking (307/341, 90.03%) and male gender (328/341, 96.19%), although young patients had fewer traditional risk factors of acute myocardial infarction than the control group [(1.63 ± 1.03) vs. (2.38 ± 1.15), p < 0.01]. The number of affected vessels in cases was significantly less than in the elder control group (p < 0.01). During the follow-up, blood lipids and blood pressure of most patients reached the target level, while 42.10% of patients reported continuation of smoking. Multivariable data analysis showed that persistence of smoking (OR: 3.784, 95% CI: 1.636-8.751, p < 0.01) was the most significant prognostic factor of cardiac events after adjusting for various confounding factors.
conclusionsWe demonstrated that cigarette smoking is the most prevalent factor among the avoidable cardiovascular risk factors for young ST-segment elevation myocardial infarctions in China. Accordingly, continued smoking is the most powerful predictor for the recurrence of cardiac events in young Chinese patients with ST-segment elevation myocardial infarction. KEY WORDS: Premature myocardial infarction; Prognosis; Risk factor.
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