ArticleActa Cardiologica Sinica2014
Factors Associated with Lipid Goal Attainment among Patients with Deployed Drug Eluting Stent.
Article in Acta Cardiologica Sinica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Determinants of Treatment Modification in Hypercholesterolemic Patients.Acta Cardiologica Sinica · 2017Article
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Authors and funding
4 authors.
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Abstract
backgroundDrug-eluting stents (DES) have provided significant benefits for patients with complex coronary lesions. Intensive lipid control through statin therapy decreases the risk of late target lesion revascularization in patients with implanted DES. Therefore, we investigated lipid management in patients with implanted DES and analyzed the predictors for achieving target lipid goals.
methodsA retrospective study was performed on consecutive patients who underwent percutaneous coronary intervention (PCI) with DES deployment from 2010 to 2012. Fasting lipid profiles were obtained for all patients both on the day of and 6 months after PCI. Logistic regression analysis was used to predict factors for achieving target lipid goals.
resultsA total of 419 patients (mean age: 62; 80% men) were included. Only 20.8% of patients achieved the target low-density lipoprotein cholesterol (LDL-C) level of < 70 mg/dL, and 61.6% of patients achieved the target LDL-C level of < 100 mg/dL. An equivalent dose of statins was statistically significant in attaining LDL-C levels of < 70 mg/dL [adjusted odds radio (AOR): 1.30; p < 0.001] and < 100 mg/dL (AOR: 1.27; p < 0.001). In addition, a baseline LDL-C level < 130 mg/dL is a leading predictor of achieving target LDL-C levels (AOR: 2.3, p = 0.012 for LDL-C < 70 mg/dL; AOR: 2.01, p = 0.006 for LDL-C < 100 mg/dL).
conclusionsAchievement of target LDL-C levels is difficult in patients with implanted DES and a baseline LDL-C level of ≥130 mg/dL who are not treated with statins. Therefore, these patients should be treated with more aggressive statin therapy. KEY WORDS: Drug-eluting stents; Low density lipoprotein.
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