ArticleBMC public health2016
Modelling the impact of alcohol consumption on cardiovascular disease mortality for comparative risk assessments: an overview.
Article in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06634771 (Frontal E/I Balance Mediation of tACS Effects on Behavioral Flexibility), which is not on this map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Frontal E/I Balance Mediation of tACS Effects on Behavioral Flexibility
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies.Addiction (Abingdon, England) · 2026Pooled it
- Moderate alcohol consumption and atherosclerosis : Meta-analysis of effects on lipids and inflammation.Wiener klinische Wochenschrift · 2017Pooled it
- The relationship between different dimensions of alcohol use and the burden of disease-an update.Addiction (Abingdon, England) · 2017Pooled it
- Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records.BMJ (Clinical research ed.) · 2017Trial
- Gut-immune-PVAT axis is involved in ethanol-induced abdominal aortic dysfunction via IL-17RA, TLR4, and FPR1 signaling.Gut microbes · 2026Article
- Impact of Alcohol Consumption on Cardiovascular Events in Patients Undergoing Percutaneous Coronary Intervention.Journal of clinical medicine · 2024Article
- Incidence and risk factors of cardiovascular disease among population aged 40-70 years: a population-based cohort study in the South of Iran.Tropical medicine and health · 2023Article
- The impact of alcohol pricing policies on public health in Hong Kong, China: A modelling study.The Lancet regional health. Western Pacific · 2022Article
- Prevalence and Correlates of Physical Comorbidities in Alcohol Use Disorder (AUD): a Pilot Study in Treatment-Seeking Population.International journal of mental health and addiction · 2022Article
- Bayesian modelling of population trends in alcohol consumption provides empirically based country estimates for South Africa.Population health metrics · 2021Article
- Review
- The association of alcohol use with all-cause and cardiovascular disease-related hospitalizations or death in older, high-risk Veterans.Alcoholism, clinical and experimental research · 2021Article
- The Role of Enjoyment in a Serious Game for Binge Drinking Prevention: Pretest-Posttest Quasi-Experimental Study.Journal of medical Internet research · 2020Article
- Lifecourse Drinking Patterns, Hypertension, and Heart Problems Among U.S. Adults.American journal of preventive medicine · 2020Article
- Alcohol Consumption in Later Life and Mortality in the United States: Results from 9 Waves of the Health and Retirement Study.Alcoholism, clinical and experimental research · 2019Article
- Effects of ethanol and ethanol metabolites on intrinsic function of mesenteric resistance arteries.PloS one · 2019Article
- Dynamic Features of Problematic Drinking: Alcohol Use Disorder Latent Classes Across Ages 18-64.Alcohol and alcoholism (Oxford, Oxfordshire) · 2019Article
- The socioeconomic profile of alcohol-attributable mortality in South Africa: a modelling study.BMC medicine · 2018Article
- Summary of the 2016 Alcohol and Immunology Research Interest Group (AIRIG) meeting.Alcohol (Fayetteville, N.Y.) · 2018Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough alcohol consumption has long been considered as a risk factor for chronic disease, the relationship to cardiovascular disease (CVD) is complex and involves at least two dimensions: average volume of alcohol consumption and patterns of drinking. The objective of this contribution was to estimate the burden of CVD mortality caused by alcohol consumption.
methodsRisk assessment modelling with alcohol-attributable CVD mortality as primary outcome. The mortality burden of ischaemic heart disease (IHD) and ischaemic stroke (IS) attributable to alcohol consumption was estimated using attributable-fraction methodology. Relative Risk (RR) data for IHD and IS were obtained from the most comprehensive meta-analyses (except for Russia and surrounding countries where alcohol RR data were obtained from a large cohort study). Age-group specific RRs were calculated, based on large studies. Data on mortality were obtained from the World Health Organization's Global Health Estimates and alcohol consumption data were obtained from the Global Information System on Alcohol and Health. Risk of former drinkers was modelled taking into account global differences in the prevalence of sick quitters among former drinkers. Alcohol-attributable mortality estimates for all other CVD causes except IHD and IS were obtained from the 2014 Global Status Report on Alcohol and Health.
resultsAn estimated 780,381 CVD deaths (441,893 and 338,490 CVD deaths among men and women respectively) were attributable to alcohol consumption globally in 2012, accounting for 1.4 % of all deaths and 26.6 % of all alcohol-attributable deaths. This is in contrast to the previously estimated 1,128,273 CVD deaths attributable to alcohol consumption globally, and represents a decrease of 30.8 % in alcohol-attributable CVD mortality and of 10.6 % in the global burden of all alcohol-attributable deaths.
conclusionsWhen the most comprehensive and recent systematic reviews and meta-analyses are taken as bases, the net impact of alcohol consumption on CVD is lower than previously estimated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.