Evidence map›Paper›PMID 27120592›Full record

ArticleMolecules (Basel, Switzerland)2016

The Unusual Acid-Accumulating Behavior during Ripening of Cherimoya (Annona cherimola Mill.) is Linked to Changes in Transcription and Enzyme Activity Related to Citric and Malic Acid Metabolism.

Mauricio González-Agüero, Luis Tejerina Pardo, María Sofía Zamudio, Carolina Contreras, Pedro Undurraga, Bruno G Defilippi

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mauricio González-AgüeroInstituto de Investigaciones Agropecuarias, INIA La Platina, Santa Rosa 11610, Santiago 8831314, Chile. maugonzalez@inia.cl.
Luis Tejerina PardoFacultad Ciencias Biológicas, Escuela de Ingeniería en Biotecnología, Universidad Andrés Bello, República 217, Santiago 8370146, Chile. ltejerinapardo@gmail.com.
María Sofía ZamudioInstituto de Investigaciones Agropecuarias, INIA La Platina, Santa Rosa 11610, Santiago 8831314, Chile. sofizamudio@gmail.com.
Carolina ContrerasInstituto de Investigaciones Agropecuarias, INIA La Platina, Santa Rosa 11610, Santiago 8831314, Chile. cdcontr1@uc.cl.
Pedro UndurragaFacultad de Agronomía, Pontificia Universidad Católica de Valparaíso, Calle San Francisco s/n, Casilla 4-D, Quillota 2260000, Chile. pundurra@ucv.cl.
Bruno G DefilippiInstituto de Investigaciones Agropecuarias, INIA La Platina, Santa Rosa 11610, Santiago 8831314, Chile. bdefilip@inia.cl.
Instituto de Investigaciones Agropecuarias · CLPontificia Universidad Católica de Valparaíso · CLUniversidad Andrés Bello · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cherimoya (Annona cherimola Mill.) is a subtropical fruit characterized by a significant increase in organic acid levels during ripening, making it an interesting model for studying the relationship between acidity and fruit flavor. In this work, we focused on understanding the balance between the concentration of organic acids and the gene expression and activity of enzymes involved in the synthesis and degradation of these metabolites during the development and ripening of cherimoya cv. "Concha Lisa". Our results showed an early accumulation of citric acid and other changes associated with the accumulation of transcripts encoding citrate catabolism enzymes. During ripening, a 2-fold increase in malic acid and a 6-fold increase in citric acid were detected. By comparing the contents of these compounds with gene expression and enzymatic activity levels, we determined that cytoplasmic NAD-dependent malate dehydrogenase (cyNAD-MDH) and mitochondrial citrate synthase (mCS) play important regulatory roles in the malic and citric acid biosynthetic pathways.

Indexed as

Gene ExpressionAcids, AcyclicAnnonaCitric AcidDNA, PlantGene Expression Regulation, PlantMalate DehydrogenaseMalatesMetabolic Networks and PathwaysPlant ProteinsSequence Analysis, DNAAcids, AcyclicCitric AcidDNA, PlantMalate DehydrogenaseMalatesmalic acidPlant ProteinsAnnona cherimolagene expressionorganic acids

Identifiers

PMID27120592
PMCPMC6273758
OpenAlexW2344545570

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.