ArticlePloS one2016
Psychotic Experiences and Working Memory: A Population-Based Study Using Signal-Detection Analysis.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Systematic reviews of the acute effects of amphetamine on working memory and other cognitive performances in healthy individuals, with a focus on the potential influence of personality traits.Human psychopharmacology · 2023Pooled it
- The effects of caffeine and d-amphetamine on spatial span task in healthy participants.PloS one · 2023Trial
- Polarity-Dependent Effects of Sinusoidal Galvanic Vestibular Stimulation on Cardiovascular Responses During Cognitive Load.Sensors (Basel, Switzerland) · 2026Article
- Working memory performance is related to childhood trauma but not psychotic-like experiences in a nonpsychiatric sample.Psychological trauma : theory, research, practice and policy · 2024Article
- Early Childhood Neurocognition in Relation to Middle Childhood Psychotic Experiences in Children at Familial High Risk of Schizophrenia or Bipolar Disorder and Population-Based Controls: The Danish High Risk and Resilience Study.Schizophrenia bulletin · 2023Article
- Speech Illusions in People at Clinical High Risk for Psychosis Linked to Clinical Outcome.Schizophrenia bulletin · 2023Article
- Cognitive Dysfunction as a Risk Factor for Psychosis.Current topics in behavioral neurosciences · 2023Article
- Positive symptoms of schizophrenia and their relationship with cognitive and emotional executive functions.Cognitive research: principles and implications · 2022Article
- Distressing psychotic-like experiences, cognitive functioning and early developmental markers in clinically referred young people aged 8-18 years.Social psychiatry and psychiatric epidemiology · 2022Article
- Correlates of Hallucinatory Experiences in the General Population: An International Multisite Replication Study.Psychological science · 2021Article
- Examining Specificity of Neural Correlates of Childhood Psychotic-like Experiences During an Emotional n-Back Task.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020Article
- Replication of Associations With Psychotic-Like Experiences in Middle Childhood From the Adolescent Brain Cognitive Development (ABCD) Study.Schizophrenia bulletin open · 2020Article
- Atypical response inhibition and error processing in 22q11.2 Deletion Syndrome and schizophrenia: Towards neuromarkers of disease progression and risk.NeuroImage. Clinical · 2020Article
- ResilienCity: Resilience and Psychotic-Like Experiences 10 Years After L'Aquila Earthquake.Frontiers in psychiatry · 2020Article
- The emergence of psychotic experiences in the early adolescence of 22q11.2 Deletion Syndrome.Journal of psychiatric research · 2019Article
- Altered segregation between task-positive and task-negative regions in mild traumatic brain injury.Brain imaging and behavior · 2018Article
- Speech illusions and working memory performance in non-clinical psychosis.Schizophrenia research · 2018Article
- Alcohol Use in Adolescence and Later Working Memory: Findings From a Large Population-Based Birth Cohort.Alcohol and alcoholism (Oxford, Oxfordshire) · 2018Article
- The interaction between subclinical psychotic experiences, insomnia and objective measures of sleep.Schizophrenia research · 2018Article
Corrections and comments
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Authors and funding
6 authors at 6 institutions in 2 countries.
Funding
Abstract
Psychotic Experiences (PEs) during adolescence index increased risk for psychotic disorders and schizophrenia in adult life. Working memory (WM) deficits are a core feature of these disorders. Our objective was to examine the relationship between PEs and WM in a general population sample of young people in a case control study. 4744 individuals of age 17-18 from Bristol and surrounding areas (UK) were analyzed in a cross-sectional study nested within the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort study. The dependent variable was PEs, assessed using the semi-structured Psychosis-Like Symptom Interview (PLIKSi). The independent variable was performance on a computerized numerical n-back working memory task. Signal-Detection Theory indices, including standardized hits rate, false alarms rate, discriminability index (d') and response bias (c) from 2-Back and 3-Back tasks were calculated. 3576 and 3527 individuals had complete data for 2-Back and 3-Back respectively. Suspected/definite PEs prevalence was 7.9% (N = 374). Strongest evidence of association was seen between PEs and false alarms on the 2-Back, (odds ratio (OR) = 1.17 [95% confidence intervals (CI) 1.01, 1.35]) and 3-back (OR = 1.35 [1.18, 1.54]) and with c (OR = 1.59 [1.09, 2.34]), and lower d' (OR = 0.76 [0.65, 0.89]), on the 3-Back. Adjustment for several potential confounders, including general IQ, drug exposure and different psycho-social factors, and subsequent multiple imputation of missing data did not materially alter the results. WM is impaired in young people with PEs in the general population. False alarms, rather than poor accuracy, are more closely related to PEs. Such impairment is consistent with different neuropsychological models of psychosis focusing on signal-to-noise discrimination, probabilistic reasoning and impaired reality monitoring as a basis of psychotic symptoms.
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