ArticleNature2016
Principles underlying sensory map topography in primary visual cortex.
Article in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 159 citations in OpenAlex.
- A unifying principle of chromatic coding across biological and artificial systems.Science advances · 2026Article
- The cortical canvas.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Human accommodative visuomotor function is driven by contrast through ON and OFF pathways and is enhanced in myopia.Cell reports · 2026Article
- Optogenetic stimulation of pyramidal neurons in the rat primary visual cortex modulates ON- and OFF- receptive field areas independently.Scientific reports · 2025Article
- Do the receptive fields in the primary visual cortex span a variability over the degree of elongation of the receptive fields?Journal of computational neuroscience · 2025Article
- Article
- Orientation selectivity properties for the affine Gaussian derivative and the affine Gabor models for visual receptive fields.Journal of computational neuroscience · 2025Article
- Cortical direction selectivity increases from the input to the output layers of visual cortex.PLoS biology · 2025Article
- Identification of movie encoding neurons enables movie recognition AI.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Good vision without peripheries: behavioral and fMRI evidence.Scientific reports · 2024Article
- Article
- Visual neurons recognize complex image transformations.bioRxiv : the preprint server for biology · 2024Article
- Binocular receptive-field construction in the primary visual cortex.Current biology : CB · 2024Article
- Nonuniform and pathway-specific laminar processing of spatial frequencies in the primary visual cortex of primates.Nature communications · 2024Article
- Efficient mapping of the thalamocortical monosynaptic connectivity in vivo by tangential insertions of high-density electrodes in the cortex.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Understanding contrast perception in amblyopia: a psychophysical analysis of the ON and OFF visual pathways.Frontiers in psychology · 2024Article
- Stimulus edges induce orientation tuning in superior colliculus.Nature communications · 2023Article
- Dynamic Recruitment of the Feedforward and Recurrent Mechanism for Black-White Asymmetry in the Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Retinal waves align the concentric orientation map in mouse superior colliculus to the center of vision.Science advances · 2023Article
- Differences in visual stimulation between reading and walking and implications for myopia development.Journal of vision · 2023Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The primary visual cortex contains a detailed map of the visual scene, which is represented according to multiple stimulus dimensions including spatial location, ocular dominance and stimulus orientation. The maps for spatial location and ocular dominance arise from the spatial arrangement of thalamic afferent axons in the cortex. However, the origins of the other maps remain unclear. Here we show that the cortical maps for orientation, direction and retinal disparity in the cat (Felis catus) are all strongly related to the organization of the map for spatial location of light (ON) and dark (OFF) stimuli, an organization that we show is OFF-dominated, OFF-centric and runs orthogonal to ocular dominance columns. Because this ON-OFF organization originates from the clustering of ON and OFF thalamic afferents in the visual cortex, we conclude that all main features of visual cortical topography, including orientation, direction and retinal disparity, follow a common organizing principle that arranges thalamic axons with similar retinotopy and ON-OFF polarity in neighbouring cortical regions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.