Evidence map›Paper›PMID 27119958›Full record

ReviewDer Urologe. Ausg. A2016

[Side effect management of tyrosine kinase inhibitors in urology : Fatigue and hypothyroidism].

D Sikic, G Lüdecke, V Lieb, B Keck

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Urologe. Ausg. A, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

D SikicUrologische Universitätsklinik Erlangen, Universitätsklinikum Erlangen, Rathsberger Str. 57, 91054, Erlangen, Deutschland.
G LüdeckeUrologische Universitätsklinik Gießen, Justus-Liebig Universität Gießen, Gießen, Deutschland.
V LiebUrologische Universitätsklinik Erlangen, Universitätsklinikum Erlangen, Rathsberger Str. 57, 91054, Erlangen, Deutschland.
B KeckUrologische Universitätsklinik Erlangen, Universitätsklinikum Erlangen, Rathsberger Str. 57, 91054, Erlangen, Deutschland. bastian.keck@uk-erlangen.de.
Universitätsklinikum Erlangen · DEUniversity of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Not only has the use of tyrosine kinase inhibitors (TKI) for the treatment of metastatic renal cell carcinomas (mRCC) changed the therapeutic options for this disease significantly, but with the occurrence of typical side effects this therapy also poses a challenge for the treating physician. Fatigue und hypothyroidism are two common side effects of TKI therapy that can often appear simultaneously. By reducing the patients' quality of life these side effects often lead to a discontinuation of therapy. With this review we want to give the treating physician an overview of the classification and the specific treatment of TKI-induced fatigue and hypothyroidism in order to maximize patients' compliance and the therapeutic efficacy of TKI therapy.

Indexed as

AnilidesAntineoplastic AgentsAxitinibCarcinoma, Renal CellDisease ProgressionEnzyme InhibitorsFatigueHumansHypothyroidismImidazolesIndazolesIndolesKidney NeoplasmsNeoplasm StagingNiacinamidePhenylurea CompoundsAnilidesAntineoplastic AgentsAxitinibcabozantinibEnzyme InhibitorsImidazolesIndazolesIndolesNiacinamidepazopanibPhenylurea CompoundsProtein-Tyrosine KinasesPyridinesPyrimidinesPyrrolesSorafenibSulfonamidesSunitinibAxitinibCabozantinibPazopanibSorafenibSunitinib

Identifiers

PMID27119958
OpenAlexW2433740506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.