ReviewBiophysical journal2016
DNA Nanostructures on Membranes as Tools for Synthetic Biology.
Review in Biophysical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 83 citations in OpenAlex.
- Martini 3 Coarse-Grained Model of DNA for Heterogeneous Molecular Systems.bioRxiv : the preprint server for biology · 2026Article
- Bacteriophage-Mimetic DNA Origami Needle for Targeted Membrane Penetration and Cytosolic Cargo Delivery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cation-Controlled Assembly, Activity, and Organization of Biomimetic DNA Receptors in Synthetic Cell Membranes.Journal of the American Chemical Society · 2025Article
- Morphology remodelling and membrane channel formation in synthetic cells via reconfigurable DNA nanorafts.Nature materials · 2025Article
- DNA origami: Interrogating the nano-landscape of immune receptor activation.Biophysical journal · 2024Review
- Dynamic Fusion of Nucleic Acid Functionalized Nano-/Micro-Cell-Like Containments: From Basic Concepts to Applications.ACS nano · 2023Review
- All-Atom Molecular Dynamics Simulations of Membrane-Spanning DNA Origami Nanopores.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Binding and Characterization of DNA Origami Nanostructures on Lipid Membranes.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Actuating tension-loaded DNA clamps drives membrane tubulation.Science advances · 2022Article
- Modulating membrane fusion through the design of fusogenic DNA circuits and bilayer composition.Soft matter · 2022Article
- DNA-Liposome Hybrid Carriers for Triggered Cargo Release.ACS applied bio materials · 2022Article
- Article
- Amphiphilic DNA nanostructures for bottom-up synthetic biology.Chemical communications (Cambridge, England) · 2021Review
- Clustering of catalytic nanocompartments for enhancing an extracellular non-native cascade reaction.Chemical science · 2021Article
- Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment.Nature communications · 2021Article
- Review
- Hydrophobic Interactions between DNA Duplexes and Synthetic and Biological Membranes.Journal of the American Chemical Society · 2021Article
- Choice of fluorophore affects dynamic DNA nanostructures.Nucleic acids research · 2021Article
- DNA Nanodevices to Probe and Program Membrane Organization, Dynamics, and Applications.The Journal of membrane biology · 2020Review
- Extending the Capabilities of Molecular Force Sensors via DNA Nanotechnology.Critical reviews in biomedical engineering · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last decade, functionally designed DNA nanostructures applied to lipid membranes prompted important achievements in the fields of biophysics and synthetic biology. Taking advantage of the universal rules for self-assembly of complementary oligonucleotides, DNA has proven to be an extremely versatile biocompatible building material on the nanoscale. The possibility to chemically integrate functional groups into oligonucleotides, most notably with lipophilic anchors, enabled a widespread usage of DNA as a viable alternative to proteins with respect to functional activity on membranes. As described throughout this review, hybrid DNA-lipid nanostructures can mediate events such as vesicle docking and fusion, or selective partitioning of molecules into phase-separated membranes. Moreover, the major benefit of DNA structural constructs, such as DNA tiles and DNA origami, is the reproducibility and simplicity of their design. DNA nanotechnology can produce functional structures with subnanometer precision and allow for a tight control over their biochemical functionality, e.g., interaction partners. DNA-based membrane nanopores and origami structures able to assemble into two-dimensional networks on top of lipid bilayers are recent examples of the manifold of complex devices that can be achieved. In this review, we will shortly present some of the potentially most relevant avenues and accomplishments of membrane-anchored DNA nanostructures for investigating, engineering, and mimicking lipid membrane-related biophysical processes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.