ReviewPerioperative medicine (London, England)2016
Predicting, preventing, and identifying delirium after cardiac surgery.
Review in Perioperative medicine (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07598019 (Effects of Remimazolam on Neurocognitive Function in Patients Undergoing Cardiovascular Surgery), which is not on this map. Cited by 27 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Remimazolam on Neurocognitive Function in Patients Undergoing Cardiovascular Surgery (the EFFICACY Study)
Who cites it
27 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Dexmedetomidine for the prevention of postoperative delirium in patients undergoing cardiac surgery: a systematic review and meta-analysis with trial sequential analysis.BMC anesthesiology · 2025Pooled it
- The effect of perioperative dexmedetomidine on postoperative delirium in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis of randomized controlled trials.BMC anesthesiology · 2024Pooled it
- Risk factors of postoperative delirium after cardiac surgery: a meta-analysis.Journal of cardiothoracic surgery · 2021Pooled it
- Prevention of postoperative delirium in elderly patients planned for elective surgery: systematic review and meta-analysis.Clinical interventions in aging · 2019Pooled it
- Meta-analysis of Prevalence and Risk Factors for Delirium After Transcatheter Aortic Valve Implantation.The American journal of cardiology · 2018Pooled it
- Processed Electroencephalogram Monitoring and Postoperative Delirium: A Systematic Review and Meta-analysis.Anesthesiology · 2018Pooled it
- Effect of Preoperative Beta-Blocker Use on Outcomes Following Cardiac Surgery.The American journal of cardiology · 2017Trial
- Admission lactate at ICU entry and the risk of postoperative delirium after cardiac surgery: a retrospective cohort study using the eICU-CRD database.BMC cardiovascular disorders · 2026Article
- Prediction of postoperative delirium after cardiac surgery by the interplay between preoperative plasma p-tau181 and IL-6 and heart-brain axis related factors: results from the prospective observational study FINDERI.Molecular psychiatry · 2026Observational
- Article
- Delirium after cardiac surgery incidence and perioperative risk factors in a prospective cohort.Journal of cardiothoracic surgery · 2026Article
- Soluble Urokinase Plasminogen Activator Receptor (suPAR) Plasma Concentration Is Reduced Using Minimized Extracorporeal Circulation: Results of a Secondary Analysis of a Prospective Observational Study.Journal of clinical medicine · 2025Article
- Prevalence of and risk factors for postoperative delirium among children after cardiac surgery in a Single-Centre retrospective study.Scientific reports · 2025Article
- Effect of dexmedetomidine on postoperative delirium in patients undergoing type A aortic dissection surgery: a prospective cohort study.Journal of thoracic disease · 2025Article
- National outcomes for dementia patients undergoing cardiac surgery in a pre-structural era.Journal of cardiothoracic surgery · 2024Article
- Machine learning with clinical and intraoperative biosignal data for predicting postoperative delirium after cardiac surgery.iScience · 2024Article
- Optimization of the cardiac delirium index by including age, decrease in butyrylcholinesterase actitivity, preoperative HbA1c, and postoperative hemoglobin levels: results of a secondary analysis of a prospective observational study.Frontiers in cardiovascular medicine · 2024Article
- Delirium in older adults after percutaneous coronary intervention: Prevalence, risks, and clinical phenotypes.Cardiovascular revascularization medicine : including molecular interventions · 2023Article
- Postoperative delirium: identifying the patient at risk and altering the course: A narrative review.European journal of anaesthesiology and intensive care · 2023Review
- Intraoperative Glycemic Variability and Mean Glucose are Predictors for Postoperative Delirium After Cardiac Surgery: A Retrospective Cohort Study.Clinical interventions in aging · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Delirium after cardiac surgery is a major problem. The exact mechanisms behind delirium are not understood. Potential pathways of delirium include neurotransmitter interference, global cognitive disorder, and neuroinflammation. Several predisposing and precipitating risk factors have been identified for postoperative delirium. The development of delirium following cardiac surgery is associated with worse outcomes in the perioperative period. Multiple interventions are being explored for the prevention and treatment of delirium. Studies investigating the potential roles of biomarkers in delirium as well as pharmacological interventions to reduce the incidence and duration of delirium are necessary to mitigate this negative outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.