Evidence map›Paper›PMID 27118965›Full record

ArticleComputational intelligence and neuroscience2016

MEG Analysis of Neural Interactions in Attention-Deficit/Hyperactivity Disorder.

Amine Khadmaoui, Carlos Gómez, Jesús Poza, Alejandro Bachiller, Alberto Fernández, Javier Quintero, Roberto Hornero

Abstract read
In one paragraph

Article in Computational intelligence and neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Atypical cortical networks in children at high-genetic risk of psychiatric and neurodevelopmental disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amine KhadmaouiBiomedical Engineering Group, E.T.S. Ingenieros de Telecomunicación, Universidad de Valladolid, Campus Miguel Delibes, Paseo Belén 15, 47011 Valladolid, Spain.
Carlos GómezBiomedical Engineering Group, E.T.S. Ingenieros de Telecomunicación, Universidad de Valladolid, Campus Miguel Delibes, Paseo Belén 15, 47011 Valladolid, Spain.
Jesús PozaBiomedical Engineering Group, E.T.S. Ingenieros de Telecomunicación, Universidad de Valladolid, Campus Miguel Delibes, Paseo Belén 15, 47011 Valladolid, Spain; IMUVA, Instituto de Investigación en Matemáticas, Universidad de Valladolid, Campus Miguel Delibes, Paseo Belén 7, 47011 Valladolid, Spain.
Alejandro BachillerBiomedical Engineering Group, E.T.S. Ingenieros de Telecomunicación, Universidad de Valladolid, Campus Miguel Delibes, Paseo Belén 15, 47011 Valladolid, Spain.
Alberto FernándezDepartment of Psychiatry, Facultad de Medicina, Universidad Complutense de Madrid, Ciudad Universitaria, 28040 Madrid, Spain; Laboratory of Cognitive and Computational Neuroscience, Centro de Tecnología Biomédica, Campus Montegancedo, Pozuelo de Alarcón, 28223 Madrid, Spain.
Javier QuinteroDepartment of Psychiatry, Facultad de Medicina, Universidad Complutense de Madrid, Ciudad Universitaria, 28040 Madrid, Spain; Psychiatry Service, Hospital Infanta Leonor, Avenida Gran Vía del Este 80, 28031 Madrid, Spain.
Roberto HorneroBiomedical Engineering Group, E.T.S. Ingenieros de Telecomunicación, Universidad de Valladolid, Campus Miguel Delibes, Paseo Belén 15, 47011 Valladolid, Spain; IMUVA, Instituto de Investigación en Matemáticas, Universidad de Valladolid, Campus Miguel Delibes, Paseo Belén 7, 47011 Valladolid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to explore the interchannel relationships of resting-state brain activity in patients with attention-deficit/hyperactivity disorder (ADHD), one of the most common mental disorders that develop in children. Magnetoencephalographic (MEG) signals were recorded using a 148-channel whole-head magnetometer in 13 patients with ADHD (range: 8-12 years) and 14 control subjects (range: 8-13 years). Three complementary measures (coherence, phase-locking value, and Euclidean distance) were calculated in the conventional MEG frequency bands: delta, theta, alpha, beta, and gamma. Our results showed that the interactions among MEG channels are higher for ADHD patients than for control subjects in all frequency bands. Statistically significant differences were observed for short-distance values within right-anterior and central regions, especially at delta, beta, and gamma-frequency bands (p < 0.05; Mann-Whitney U test with false discovery rate correction). These frequency bands also showed statistically significant differences in long-distance interactions, mainly among anterior and central regions, as well as among anterior, central, and other areas. These differences might reflect alterations during brain development in children with ADHD. Our results support the role of frontal abnormalities in ADHD pathophysiology, which may reflect a delay in cortical maturation in the frontal cortex.

Indexed as

MagnetoencephalographyAttention Deficit Disorder with HyperactivityChildFemaleHumansMaleNeural PathwaysSignal Processing, Computer-Assisted

Identifiers

PMID27118965
PMCPMC4828555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.