Evidence map›Paper›PMID 27118783›Full record

ArticleJournal of biochemistry2016

Roles of subunit NuoL in the proton pumping coupling mechanism of NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli.

Madhavan Narayanan, Joseph A Sakyiama, Mahmoud M Elguindy, Eiko Nakamaru-Ogiso

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Mutations inCells · 2019
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Madhavan NarayananJohnson Research Foundation, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, 422 Curie Boulevard, Philadelphia, PA 19104, USA.
Joseph A SakyiamaJohnson Research Foundation, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, 422 Curie Boulevard, Philadelphia, PA 19104, USA.
Mahmoud M ElguindyJohnson Research Foundation, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, 422 Curie Boulevard, Philadelphia, PA 19104, USA.
Eiko Nakamaru-OgisoJohnson Research Foundation, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, 422 Curie Boulevard, Philadelphia, PA 19104, USA eikoo@mail.med.upenn.edu.
Johnson Foundation · USUniversity of Pennsylvania · US

Funding

Proton pumping mechanism in complex IR01GM097409 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI OGISO, EIKO · 2011 to 2015
$1.5M
NIGMS NIH HHS R01 GM097409
6 · The paper itself

Abstract

Respiratory complex I has an L-shaped structure formed by the hydrophilic arm responsible for electron transfer and the membrane arm that contains protons pumping machinery. Here, to gain mechanistic insights into the role of subunit NuoL, we investigated the effects of Mg

Indexed as

AmilorideCell MembraneElectron Transport Complex IEscherichia coliEscherichia coli ProteinsMutationNADH DehydrogenaseAmilorideElectron Transport Complex IEscherichia coli ProteinsethylisopropylamilorideNADH DehydrogenaseNuoL protein, E colicomplex Ienergy couplingmenaquinoneproton pumpingubiquinone

Identifiers

PMID27118783
PMCPMC5048018
OpenAlexW2342891081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.